Transforming growth factor beta (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily that includes three [1] different mammalian isoforms …

TGF-α is a transforming growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This …

2024年3月22日 · Transforming growth factor (TGF)-β is a multifunctional cytokine expressed by almost every tissue and cell type. The signal transduction of TGF-β can stimulate diverse...

TGF-β signaling controls metazoan embryo development, tissue homeostasis, and injury repair through coordinated effects on cell proliferation, phenotypic plasticity, migration, metabolic …

转化生长因子β (transforming growth factor-β，TGF-β)是血管再狭窄中重要的调控分子，在血管再狭窄的发生、发展中发挥关键作用。 TGF-β是TGF-β超家族成员之一，可与TGF-β受体相结 …

2016年4月25日 · Inhibition of the TGF-β isoform, TGF-β1, or its downstream signalling pathways substantially limits renal fibrosis in a wide range of disease models whereas overexpression of …

2016年12月20日 · 转化生长因子-β (transforming growth factor-β, TGF-β)在细胞的自我调控包括细胞增殖、分化、凋亡、胚胎发育、免疫监督、血管再生等过程中发挥重要作用。 TGF-βⅢ型受 …

结论OM作用于HS成纤维细胞可产生抑制效应，其部分机制是通过TGF—β—Smad信号通路的负性调节，实现对细胞的胶原合成及收缩功能的抑制。 Skip to search form Skip to main content …

2010年12月22日 · The long form of Latent TGF-β binding protein 1 (LTBP1L) covalently binds all TGF-β isoforms and regulates their bioavailability. Ltbp1L expression analysis during …

TGF-beta ligands are initially synthesized as precursor proteins that undergo proteolytic cleavage. The mature segments form dimers via disulfide links (except for GDF-3, -9, BMP-15, and …