2024年12月25日 · TGFBR1 (Transforming Growth Factor Beta Receptor 1) is a Protein Coding gene. Diseases associated with TGFBR1 include Multiple Self-Healing Squamous Epithelioma …

Transforming growth factor beta receptor I (activin A receptor type II-like kinase, 53kDa) is a membrane-bound TGF beta receptor protein of the TGF-beta receptor family for the TGF beta …

The TGFBR1 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 1. This receptor transmits signals from the cell surface into the cell …

TGF-β的命名是根据这种细胞因子能使正常的成纤维细胞的表型发生转化，即在表皮生长因子（EGF）同时存在的条件下，改变成纤维细胞贴壁生长特性而获得在琼脂中生长的能力，并失 …

High TGFBR1 expression is associated with epithelialtomesenchymal transition and metastasis in breast cancer. polymorphism of TGFBR1 rs334348 may act as a potentially independent …

2011年10月20日 · We identified a novel role for a TGFβ receptor (called TGFBR1) in female fertility. We demonstrated that female mice with disruption of Tgfbr1 in the reproductive tract …

TGFB1 regulates cell cycle progression by a unique signaling mechanism that involves its binding to TGFBR2 and activation of TGFBR1. Both are transmembrane serine/threonine receptor …

由该基因编码的蛋白质在与 TGF-β 结合时与 II 型 TGF-β 受体形成异聚复合物，将 TGF-β 信号从细胞表面转导至细胞质。 编码的蛋白质是丝氨酸/苏氨酸蛋白激酶。 该基因的突变与 Loeys …

2025年1月4日 · Go to complete Gene record for TGFBR1; Go to Variation Viewer for TGFBR1 variants; Summary. The protein encoded by this gene forms a heteromeric complex with type …

TGFBR1 mutation Gln-487 has been reported to be associated with thoracic aortic aneurysms and dissection (TAAD) (PubMed:16791849). This phenotype, also known as thoracic aortic …