2021年4月14日 · This review considers recent advances reported in the field of TSP1-CD47 signalling, focusing on several aspects including enzymatic production, receptor function, interacting partners, localization of signalling, matrix-cellular and cell-to-cell cross talk.

2022年11月21日 · 该研究利用单细胞质谱流式细胞术确定了CD47高表达是功能障碍的肌肉干细胞的标志，并进一步确定了血小板反应蛋白-1（THBS1）与肌肉干细胞表面的CD47结合，从而抑制肌肉干细胞活性。

2023年9月25日 · Our study establishes THBS1 as a potential biomarker for identifying mesenchymal CRC and as a critical suppressor of antitumor immunity that contributes to the progression of this malignancy with...

2021年2月18日 · Liquid chromatography tandem mass spectrometry and STRING functional protein association network analyses predicted that THBS1/CD47 modulated the interaction between γ-catenin and E-cadherin and was involved in epithelial-mesenchymal transition, which was supported by immunoprecipitation and immunohistochemistry.

2016年1月27日 · These data demonstrate that thrombospondin-1 exerts CD47-dependent and -independent pro-and anti-inflammatory effects on the IL-1β pathway. Therefore, thrombospondin-1 and its receptor CD47 may...

Liquid chromatography tandem mass spectrometry and STRING functional protein association network analyses predicted that THBS1/CD47 modulated the interaction between γ-catenin and E-cadherin and was involved in epithelial–mesenchymal transition, which was supported by immunoprecipitation and immunohistochemistry.

Liquid chromatography tandem mass spectrometry and STRING functional protein association network analyses predicted that THBS1/CD47 modulated the interaction between γ-catenin and E-cadherin and was involved in epithelial–mesenchymal transition, which was supported by immunoprecipitation and immunohistochemistry.

THBS1 binding to CD36 and CD47 receptors can play different roles in TME, and THBS1 interacts with CD47 on immune cells, thus inactivating anti-tumor immune surveillance, which may attenuate the anti-tumor effect of M1 polarized macrophages in GC 31 and CD36 could promote the activation of M2 macrophages and also promote the migration and ...

THBS1通过与CD36和CD47等受体结合，激活相关信号通路，影响肿瘤微环境中的免疫细胞活性和血管生成 。 THBS1在肿瘤微环境中扮演着复杂的角色。

2021年2月17日 · Liquid chromatography tandem mass spectrometry and STRING functional protein association network analyses predicted that THBS1/CD47 modulated the interaction between γ-catenin and E-cadherin and was involved in epithelial–mesenchymal transition, which was supported by immunoprecipitation and immunohistochemistry.