TRIM25 Promotes TNF-α-Induced NF-κB Activation through ... - PubMed
2020年3月15日 · In the current study, we identified TRIM25, an E3 ubiquitin ligase, as a novel positive regulator in mediating NF-κB activation in human embryonic kidney 293T (HEK293T), …
Inhibition of transmembrane TNF-α shedding by a specific …
2019年8月5日 · In this study, we show that this antibody can specifically suppress tmTNF-α shedding by competing with a TNF-α converting enzyme that cleaves the tmTNF-α …
TRIM25 Promotes TNF-α–Induced NF-κB Activation through …
2020年3月15日 · In the current study, we identified TRIM25, an E3 ubiquitin ligase, as a novel positive regulator in mediating NF-κB activation in human embryonic kidney 293T (HEK293T), …
TNFα regulates the expression of the CSE gene in HUVEC
Therefore, the present study investigated the role of the NF-κB transcription factor binding site in the transcriptional regulation of the CSE gene in 293T cells following treatment with TNFα …
Stat1 as a Component of Tumor Necrosis Factor Alpha Receptor 1 …
Consistently in 293T cells, transient overexpression of Stat1 blocked NF-κB activation by TNF-α. Therefore, by binding to the TNFR1-TRADD signaling complex, Stat1 favors DISC formation …
吉满生物NFKB Reporter HEK-293 Cell Line 是一种Luciferase 报告基因细胞系。当TNF-α结合受体后，激活下游信号通路，从而激活荧光素酶（Luciferase）的表达。Luciferase 读 值即代表信 …
Recombinant Human TNF-alpha (HEK293-expressed) Protein, …
Recombinant Human TNF‑ alpha (HEK293-expressed) (Catalog # 10291-TA) induces cytotoxicity in the L‑929 mouse fibroblast cell line in the presence of the metabolic inhibitor actinomycin D. …
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Overexpression of CD14, TLR4, and MD-2 in HEK 293T cells does …
Human HEK 293T cells are completely unresponsive to LPS, but acquire high LPS sensitivity following transient transfection with CD14, TLR4, and MD-2 (293T/CD14/TLR4/MD-2 cells), as …
在HEK 293细胞中表达的HumanKine人重组TNF-a（肿瘤坏死因子 …
肿瘤坏死因子-α （TNF-α）在人HEK 293细胞中表达，且已证明其主要以糖基化、非共价连接的同源三聚体存在，分子量为51kDa（凝胶过滤）。 在人293细胞中生成可提供真正的糖基化。 糖 …
The CellSensor® NFκB-bla HEK 293T cell line contains a beta-lactamase reporter gene under control of the Nuclear Factor Kappa Beta (NFκB) response element stably integrated into HEK …