
3分钟带你了解硫氧还蛋白还原酶 - 每日生物评论
2020年1月15日 · TrxR与谷胱甘肽还原酶(GR)活性类似,催化GSSG还原生成GSH,是谷胱甘肽氧化还原循环关键酶之一。 TrxR是一种NADPH依赖的包含FAD结构域的二聚体硒酶,属于 …
Redox Signaling Mediated by Thioredoxin and Glutathione …
2021年11月1日 · This review will focus on the roles of Trx and GSH in regulating redox signaling in the CNS and the effects of redox-active compounds in neuronal disorders via the Trx and …
3分钟带你了解硫氧还蛋白还原酶 - 知乎
TrxR与谷胱甘肽还原酶(GR)活性类似,催化GSSG还原生成GSH,是谷胱甘肽氧化还原循环关键酶之一。 TrxR是一种NADPH依赖的包含FAD结构域的二聚体硒酶,属于吡啶核…
Redox regulation of immunometabolism
2020年12月18日 · Two main cellular antioxidant pathways, namely the TRX and GSH/glutaredoxin (GRX) systems, have the capacity to provide the reducing power to RNR, …
Regulation of the redox homeostasis by glutathione (GSH), …
Hydrogen peroxide (H2O2) and hydroperoxides (ROOH) are catalyzed by GSH peroxidase (GPx) or peroxiredoxin (Prx) to alcohols (ROH) and water. The oxidized form of Trx is reduced back …
The thioredoxin antioxidant system - PubMed
The Trx system provides the electrons to thiol-dependent peroxidases (peroxiredoxins) to remove reactive oxygen and nitrogen species with a fast reaction rate. Trx antioxidant functions are …
The thioredoxin antioxidant system - ScienceDirect
2014年1月8日 · In mammalian cells, the cytosolic and mitochondrial Trx systems, in which TrxRs are high molecular weight selenoenzymes, together with the glutathione-glutaredoxin (Grx) …
EXTH-35。胶质母细胞干细胞中靶向硫氧还蛋白还原酶(TRX1)和谷胱甘肽系统(GSH…
我们使用GSH抑制剂ROS诱导剂L-Buthionine Sulfoxamine(L-BSO)展示了ROS在响应Au中的作用,和ROS清除剂N-乙酰半胱氨酸(NAc)。 L-BSO与Au的结合大大降低了纳摩尔浓度范围 …
Redox Signaling Mediated by Thioredoxin and Glutathione
2017年11月1日 · Significance: The thioredoxin (Trx) and glutathione (GSH) systems play important roles in maintaining the redox balance in the brain, a tissue that is prone to oxidative …
Thioredoxin and glutaredoxin systems in plants: molecular …
2012年10月15日 · Cytosolic Trxs are reduced by NADPH-thioredoxin reductase (NTR), while the reduction of Grx depends on reduced glutathione (GSH). Interestingly, recent development …
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