2024年6月7日 · A tissue transglutaminase IgA test or tTg-IgA test is an effective method used in the diagnosis of celiac disease. It is a blood test that checks for antibodies or immunoglobulins, which...

For most children and adults, the best way to test for celiac disease is with the Tissue Transglutaminase IgA antibody (tTG-IgA), plus an IgA antibody in order to ensure that the patient generates enough of this antibody to render the celiac disease test accurate.

The tTG-IgA test is the preferred celiac disease serologic test for most patients. 1 Research suggests that the tTG-IgA test has a sensitivity of 78% to 100% and a specificity of 90% to 100%. 2 The performance of this test may depend on the degree of intestinal damage, making the test less sensitive in patients who have mild celiac disease.

2021年12月20日 · Tissue transglutaminase test (also known as IgA Anti-tTG test, celiac disease testing and IgA anti-tissue transglutaminase test)is a serological test used for screening and detecting celiac disease and a related skin disorder dermatitis herpetiformis.

Tissue transglutaminase is the most specific test for Coeliac Disease. Gluten-sensitive patients react to Gliadin (found in wheat, barley and rye gluten) and to an antigenic component of the gut endomysium, now known to be tissue Transglutaminase (tTg),

Your tTG IgA and IgG test results will typically fall into one of two categories: positive or negative. A positive result indicates the presence of tTG antibodies in your blood, suggesting an autoimmune condition like celiac disease .

2024年1月20日 · In individuals with celiac disease, the ingestion of gluten triggers an immune response, leading to the production of antibodies, including tTG-IgA. These antibodies target the tissues of the small intestine, causing damage and inflammation. The tTG-IgA test measures the levels of these specific antibodies in the blood.