IBCC – Thrombotic microangiopathies (TTP, HUS, et al.) - EMCrit …
2021年5月6日 · Thrombotic thrombocytopenic purpura (TTP) remains an important hematologic emergency that must be promptly recognized. This chapter attempts to disentangle these …
Thrombotic microangiopathies (including TTP, ST-HUS, and C …
2024年9月24日 · [#3] TTP. Epidemiology: TTP tends to occur in the second or third trimester. However, if thrombotic microangiopathy occurs in the first trimester, TTP is the most likely …
Thrombocytopenia - EMCrit Project
2024年9月21日 · Thrombocytopenia (<150,000 platelets) is extremely common in the ICU. It is often a poor prognostic sign that is associated with systemic inflammation. Most cases of …
Expert statement on the ICU management of patients with
Thrombotic thrombocytopenic purpura (TTP) is fatal in 90% of patients if left untreated and must be diagnosed early to optimize patient outcomes. However, the very low incidence of TTP is …
Thrombotic Thrombocytopenic Purpura and Hemolytic Uremic …
Thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS) are multisystemic disorders that are characterized by thrombocytopenia, microangiopathic …
Management of immune thrombotic thrombocytopenic purpura …
2024年10月3日 · Caplacizumab with immunosuppression, but without additional TPE, is an effective and safe treatment strategy for acute iTTP. Immune thrombotic thrombocytopenic …
Thrombocytopenia in the ICU: disseminated intravascular …
2018年6月13日 · TTP is diagnosed by identification of low ADAMTS13 activity (< 5-10%) and treated urgently with plasma exchange initially; HUS is associated with normal ADAMTS13 …
Medical consult: aHUS, TTP? How to distinguish and what to do
2023年12月8日 · Immune thrombotic thrombocytopenic purpura (iTTP) caused by an autoantibody-mediated deficiency of ADAMTS13 and atypical hemolytic syndrome (aHUS) …
Thrombotic Microangiopathies - PMC
Thrombotic thrombocytopenic purpura (TTP) has classically been defined as the pentad of microangiopathic hemolytic anemia, thrombocytopenia, fever, and neurological and renal …
EM@3AM: Purpura - emDocs
2021年3月27日 · This patient has thrombotic thrombocytopenic purpura (TTP), a rare but deadly disease with an untreated mortality approaching 100%. TTP involves microangiopathic …