
Physiology, Thromboxane A2 - StatPearls - NCBI Bookshelf
2022年9月12日 · TxA2 is involved in multiple biological processes via its cell surface receptor, termed the TP. The TP is a G protein-coupled receptor (GPCR) expressed in various tissues …
Thromboxane A2 - Wikipedia
Thromboxane A2 (TXA2) is a type of thromboxane that is produced by activated platelets during hemostasis and has prothrombotic properties: it stimulates activation of new platelets as well …
血小板功能检测专题(5):花生四烯酸途径生物活性物质和COX …
2022年6月14日 · txa2促进血管收缩,血管平滑肌细胞增殖以及血小板活化。 TXA2 结合至膜受体 TPα 或 TPβ ,会导致致密管状系统( DTS )中 钙离子 的动员(Mobilization)。
Antiplatelet Therapy: Targeting the TxA2 Pathway | Journal of ...
2013年12月19日 · TxA2 mediates its effect through the thromboxane prostanoid (TP) receptor that is expressed not only in platelets, but also in endothelial cells, macrophages, and …
Thromboxane and the thromboxane receptor in cardiovascular …
Thromboxane A2 (TXA2), the primary product of COX-1-dependent metabolism of arachidonic acid, mediates its biological actions through the TXA2 receptor, termed the TP. Irreversible …
Thromboxane A2: Physiology/pathophysiology, cellular signal ...
2008年4月1日 · Thromboxane A 2 (TXA 2), an unstable arachidonic acid metabolite, elicits diverse physiological/pathophysiological actions, including platelet aggregation and smooth …
Thromboxane-induced contractile response of mesenteric …
2022年10月12日 · The thromboxane A2 (TXA2) receptor (TP) is a member of the GPCR family. The ultimate effect of TP receptor activation depends on the availability of specific G proteins, …
The thromboxane synthase and receptor signaling pathway in …
TXA 2 is responsible for multiple biological processes through its cell surface receptor, the T-prostanoid (TP) receptor. Thromboxane A 2 synthase and TP are the two necessary …
Thromboxane A2 modulates interaction of dendritic cells and T …
2003年6月1日 · Here we show that DCs produce thromboxane A 2 (TXA 2), whereas naive T cells express the thromboxane receptor (TP). In vitro, a TP agonist enhances random cell …
Antiplatelet therapy: targeting the TxA2 pathway - PubMed
TxA2 mediates its effect through the thromboxane prostanoid (TP) receptor that is expressed not only in platelets, but also in endothelial cells, macrophages, and monocytes, and thus …