2023年9月30日 · Dapagliflozin works by lowering blood sugar levels in people with type 2 diabetes by excreting extra sugar from the body through urine. Linagliptin works by increasing the amounts of certain natural substances that lower blood sugar when it is high.

Embark on a transformative journey in diabetes care with the dynamic combination of Linagliptin 5 mg and Dapagliflozin 10 mg, known as Linovio-D. In this comprehensive guide, we delve into the uses, benefits, recommended dosage, and potential side effects of this potent formulation, emphasizing the importance of Linagliptin 5 mg and ...

The study results indicate that the FDC of dapagliflozin 10 mg + linagliptin 5 mg tablets is superior to linagliptin 5 mg tablets in terms of efficacy. This FDC offers a promising and effective treatment option for the management of T2DM, leading to significant improvements in glycemic control.

Dapagliflozin and linagliptin are commonly used medications for the treatment of type-2 diabetes mellitus (T2DM) [1, 2, 3]. Dapagliflozin acts by selectively inhibiting sodium–glucose co-transporter-2 (SGLT-2) protein in the kidneys, thereby reducing renal glucose reabsorption and increasing the glucose excretion via urine [3, 4].

Dapagliflozin and linagliptin FDC (AJU-A51) showed potent glucose-lowering effects, with good tolerability, in patients with T2D who had poor glycaemic control on metformin and linagliptin (ClinicalTrials.gov [NCT06329674]).

2022年3月8日 · The results of the clinical study demonstrated comparable pharmacokinetic characteristics between IC and FCDP forms of dapagliflozin and linagliptin. The combined use of dapagliflozin and linagliptin was safe and tolerable in both formulations.

Linagliptin glucose-dependently increases insulin secretion and lowers glucagon secretion thus resulting in an overall improvement in glucose homeostasis. Dapagliflozin: Sodium-glucose cotransporter-2 (SGLT2), expressed in the proximal renal tubules, is responsible for the majority of the reabsorption of filtered glucose from the tubular lumen.

5 天之前 · Dapaglyn L 10/5 Tablet is a combination of two antidiabetic medications. Dapagliflozin works by lowering blood sugar levels in people with type 2 diabetes by excreting extra sugar from the body through urine. Linagliptin works by increasing the amounts of certain natural substances that lower blood sugar when it is high.

Linapaz D is a dipeptidyl peptidase-4 (DPP-4) inhibitor and SGLT2 inhibitor combination product indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus when treatment with both linagliptin and dapagliflozin is appropriate.

2024年4月12日 · This study aims to compare the efficacy, safety, and tolerability of combination therapy of dapagliflozin plus linagliptin versus dapagliflozin plus vildagliptin as add-on therapy in T2DM patients inadequatel …