2024年12月25日 · TBCA (Tubulin Folding Cofactor A) is a Protein Coding gene. Diseases associated with TBCA include Kenny-Caffey Syndrome and Hypoparathyroidism-Retardation-Dysmorphism Syndrome. Among its related pathways are Chaperonin-mediated protein folding and Metabolism of proteins.

Tubulin-specific chaperone A is a protein that in humans is encoded by the TBCA gene. [5] [6] [7] The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates.

2024年11月3日 · TBCA is essential for cell viability and its knockdown produces a decrease in the amount of soluble tubulin, modifications in microtubules and G1 cell cycle arrest. Title: Tubulin cofactor A gene silencing in mammalian cells induces changes in microtubule cytoskeleton, cell cycle arrest and cell death.

The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation.

Gene: TBCA. GWAS; Genes; TBCA; Gene information. Gene name-Description -Location-Cytogenetic region-Biotype-Gene in NCBI. Gene in Ensembl. Phenotype information; ... Mapped gene Reported trait Trait(s) Background trait(s) Study accession First Author PubMed ID Location; Variant and risk allele P-value P-value annotation RAF OR Beta CI

TBCA is essential for cell viability and its knockdown produces a decrease in the amount of soluble tubulin, modifications in microtubules and G1 cell cycle arrest. The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates.

TBCA tubulin folding cofactor A [ Bufo gargarizans (Asiatic toad) ] Gene ID: 122936112, updated on 22-Mar-2024

Description: Homo sapiens tubulin folding cofactor A (TBCA), transcript variant 2, mRNA. (from RefSeq NM_004607) RefSeq Summary (NM_004607): The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to ...

The TBCA (tubulin folding cofactor A) is a protein-coding gene located on chromosome 5. Tubulin-specific chaperone A is a protein that in humans is encoded by the TBCA gene. The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates.

Human Gene TBCA (ENST00000380377.9) from GENCODE V47 Description: tubulin folding cofactor A, transcript variant 2 (from RefSeq NM_004607.3) Gencode Transcript: ENST00000380377.9