2023年4月11日 · Anti-PD- (L)1 antibodies in combination with a VEGF tyrosine-kinase inhibitor (TKI) or ipilimumab are the standard-of-care first-line therapy for patients with advanced-stage clear cell renal cell...

2022年1月20日 · Combination therapies have revolutionized the first-line treatment of metastatic clear cell renal cell carcinoma (RCC). This started with the advent of dual immune checkpoint blockade using ipilimumab plus nivolumab.

2024年8月12日 · The TNM system may be used for staging of renal cell carcinoma. An older but still widely used system for staging of renal cell carcinoma in some practices is the Robson staging system.

2022年2月16日 · Stains - Renal cell carcinoma (RCC); Anti renal cell carcinoma (RCC) antibodies detect a 200 kD glycoprotein (gp200), which is a surface membrane located on the brush border of proximal renal tubules

2016年12月8日 · Sunitinib, a vascular endothelial growth factor pathway inhibitor, is an effective treatment for metastatic renal-cell carcinoma. We sought to determine the efficacy and safety of sunitinib in...

The European Association of Urology (EAU) Renal Cell Cancer (RCC) Guidelines Panel has compiled these clinical guidelines to provide urologists with evidence-based information and recommendations for the management of RCC.

2023年3月27日 · Here, we review the distinct molecular landscapes in RCC that promote immunogenic responses, discuss clinical opportunities for discovery of biomarkers that can inform therapeutic immune...

2023年5月31日 · Using a large population of cancer patients who underwent germline and somatic tumor testing, we analyzed the landscape of germline PVs in RCC genes in individuals with all cancer types. Methods: We identified patients with germline PVs in RCC genes ( VHL, FH, SDHB, MET, FLCN, BAP1 ) in the MSK-IMPACT cohort, an institutional protocol of ...

2021年6月10日 · Intra-operative cell salvage (IOCS) and leukocyte-depleted filter (LDF) are widely used and effective in saving blood. However, the safety issue concerning reinfusion of IOCS–LDF processed blood to renal cell carcinoma (RCC) patients with inferior vena cava (IVC) thrombus were inconclusive for fear of increased risk of cancer metastases.

2020年9月1日 · The NCCN Guidelines for Kidney Cancer provide multidisciplinary recommendations for diagnostic workup, staging, and treatment of patients with renal cell carcinoma (RCC). These NCCN Guidelines Insights focus on recent updates to the guidelines, including changes to certain systemic therapy recommendations for patients …