99m mTc-MDP是目前公认的较理想的骨显像剂。 通过化学吸附结合于骨骼的无机成分中的羟基磷灰石结晶(hydroxypatitecrystal)表面，此外骨内未成熟的胶原，也对 99m Tc-MDP有较高的亲和力。

Jan 6, 2022 · Technetium 99m-methyl diphosphonate (99mTc MDP) is a radiotracer used in nuclear medicine especially for bone scintigraphy. Any disease process which results in extracellular fluid expansion will lead to accumulation of this tracer.

Mar 29, 2007 · Imaging with 99m Tc-methylene diphosphonate (99m Tc-MDP) is the initial method of choice to detect skeletal metastases in cancer patients . For SPECT of the bone, metastable technetium ( 99m Tc) is tagged onto a phosphonate compound such as MDP to generate 99m Tc-MDP, which selectively concentrates in the bone.

核医学经典的骨显像剂为 99mTc-亚甲基二膦酸盐 （99mTc-MDP），经注射后随血流到达全身骨骼，通过吸附分布于羟基磷灰石晶体而使骨骼清晰显像。同时骨组织中的有机物如未成熟的骨胶原对骨显像剂有较高的亲和力，因此在成骨活性增强的区域（如：骨折修复 ...

99mTc-Methylene diphosphonate | C2H16O14P4Tc | CID 16040217 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

99mTc作为显像剂或示踪剂进入人体后，能以特异性或非特异性方式浓聚于特定的正常脏器组织或病变组织。 99mTc药物在人体内发射出具有一定穿透力的γ射线，通过SPECT对这些光子进行探测和记录，通过计算机处理从而获得脏器、组织或者病变部位的形态、位置 ...

利尿剂介入99mtc-dtpa，spect肾动态显像可以评估肾积水程度、分肾功能、协助判断梗阻的位置及性质，为治疗前评估及治疗后随访提供重要依据。 病例分析. 患者，男，54岁，因“左侧腰痛半月”入院，b超检查提示左侧输尿管上段结石并左肾重度积水。

Early diagnosis of bone metastases with 99mTc-MDP SPECT whole-body scan based on imaging radiomics, deep learning and vision Transformer classification model

Sep 10, 2023 · 本研究基于44例出现骨受累ecd患者的 99m tc-mdp全身骨显像资料，对此类人群骨骼病变特征进行了总结，结果显示患者全身多处骨骼均可受累，其中以下肢骨受累最为常见（100%），且下肢骨病变均呈双侧对称性分布（100%），病变特征为骨干和干骺端共同受累为主 ...

Dec 5, 2022 · Single photon emission computed tomography (SPECT) with 99m Tc-labeled diphosphonates, such as [99m Tc]Tc-methylene diphosphonate (MDP) is used to assess bone metastases from prostate cancer.