2024年12月25日 · This gene encodes a ubiquitous transcriptional enhancer factor that is a member of the TEA/ATTS domain family. This protein directs the transactivation of a wide …

Transcriptional enhancer factor TEF-1 also known as TEA domain family member 1 (TEAD1) and transcription factor 13 (TCF-13) is a protein that in humans is encoded by the TEAD1 gene. [ 5 …

哺乳动物TEAD蛋白家族有4种 (TEAD1-4)，分别由四种不同基因编码。 TEAD1-4功能不尽相同，但是几乎所有的组织至少表达其中一种蛋白。 结构上，TEADs包含N-端DNA结合域 (DBD) …

2021年6月15日 · As transcription factors, TEADs orchestrate gene transcription to guide development (Landin-Malt et al., 2016). The most well-known role of TEADs involves the …

TEAD proteins constitute a family of highly conserved transcription factors, characterized by a DNA-binding domain called the TEA domain and a protein-binding domain that permits …

2020年3月13日 · Hippo signaling regulates gene expression through Tead transcription factors (TFs). We show that Hippo transcriptional coactivators Yap1/Taz and the Teads have distinct …

Nuclear protein interactions involving TEADs influence the transcriptional regulation of genes involved in cell growth, tissue homeostasis, and tumorigenesis. Clearly, protein interactions for …

2017年11月1日 · TEADs are the primary transcription factors for the YAP/TAZ transcription coactivators of the Hippo pathway. TEADs play an important role in development, tissue …

2017年12月18日 · Transcriptional enhanced associate domain (TEAD) proteins are the downstream effectors of the Hippo signaling pathway that regulate cell proliferation and stem …

2016年10月10日 · TEAD proteins constitute a family of highly conserved transcription factors, characterized by a DNA-binding domain called the TEA domain and a protein-binding domain …