2024年12月25日 · TFDP1 (Transcription Factor Dp-1) is a Protein Coding gene. Diseases associated with TFDP1 include Hepatocellular Carcinoma and Colorectal Cancer. Among its related pathways are Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects and Mitotic G1 phase and G1/S transition.

2024年2月15日 · A genome-wide CRISPR knockout screen in eHAP cells using ATAC-see to fluorescently label chromatin identifies novel regulators of accessibility, such as the transcription factor TFDP1 via ...

The TFDP1 indel84 mutation generates a gain-of-function phenotype by increasing cell proliferation, migration, and invasion of colorectal cancer cells. somatic mutations in DP-1 uncouple normal control of the E2F pathway, and thus define a new mechanism that could contribute to aberrant proliferation in tumor cells

2023年6月23日 · Transcription factor Dp-1 (TFDP1), also known as DRTF1, DP1, or Dp-1, plays a vital role in various human cancers [7 - 9]. Melchor et al showed that 13q34 amplification significantly overexpressed TFDP1 protein, and TFDP1 was one of the most potential target genes in human breast cancer [10].

2023年6月30日 · The TFDP1 gene codes for the heterodimeric partner DP1 of the transcription factor E2F. E2F, principal target of the tumor suppressor pRB, plays central roles in cell proliferation by activating a group of growth-related genes.

Title: Long non‑coding RNA DILC is involved in sepsis by modulating the signaling pathway of the interleukin‑6/signal transducer and activator of transcription 3/Toll‑like receptor 4 axis. COMMD9 participates in TFDP1/E2F1 activation and plays a critical role in non-small cell lung cancer.

TFDP1 is a potential diagnostic, immunological and prognostic biomarker in pan-cancer Asian J Surg . 2024 May;47(5):2481-2483. doi: 10.1016/j.asjsur.2024.01.094.

2024年3月5日 · Expression of the TFDP1 gene in the endometrium of women with deep infiltrating endometriosis. Long non‑coding RNA DILC is involved in sepsis by modulating the signaling pathway of the interleukin‑6/signal transducer and activator of transcription 3/Toll‑like receptor 4 axis.

2023年4月23日 · transcription factor Dp-1. 7027. This gene encodes a member of a family of transcription factors that heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes.

2024年7月23日 · In order to identify transcription factors with key roles in HSPC-mediated hematopoietic reconstitution, we developed an efficient and robust CRISPR/Cas9-based in vivo genetic screen. Using this...