4 天之前 · What Are Magnificent 7 Stocks? The Magnificent Seven has emerged as a replacement for FAANG stocks. Thanks in part to the company's disruptive potential and a lack of large-scale U.S. EV...

Fab 7, located in Woodlands, Singapore, is an operational 300 mm Fab, originally owned by Chartered Semiconductor. It produces wafers at 130 nm to 40 nm on bulk CMOS and SOI processes. It has a maximum full capacity of 50,000 300 mm wafers/month (112,500 200 mm wafers/month equivalent), using 130 to 40 nm technology. [66]

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1998年5月15日 · Fab-7 is a genetically identified element of the BX-C necessary to regulate spatial transcription of the Abdominal-B (Abd-B) gene (20, 5). Using Drosophila transgenic lines with Fab-7 flanking a GAL4-driven lacZ reporter, we developed a system capable of relieving the silencing function from Fab-7 during embryogenesis. We find that such a ...

1998年5月15日 · In Drosophila embryos, Polycomb protein and the trxG protein GAGA factor colocalize at the Fab-7 DNA element of the bithorax complex. In transgenic lines, the Fab-7 element induces extensive silencing on a flanking GAL4 …

2008年4月21日 · The best-studied Fab-7 and Fab-8 boundaries flank the iab-7 enhancer and isolate it from the four promoters regulating Abd-B expression. Recently binding sites for the Drosophila homolog of the vertebrate insulator protein CTCF (dCTCF) were identified in the Fab-8 boundary and upstream of Abd-B promoter A, with no binding of CTCF to the Fab-7 ...

Our work establishes the importance of the Fab-7 boundary for insulation between 3D domains carrying different histone modifications. Interestingly, we detect a non-canonical inversion of collinear chromatin dynamics at Abd-B, with the domain of active histone modifications progressively decreasing in size.

We propose that specialized DNA elements, such as the Fab-7 attenuator, might play a general role in controlling the levels of gene expression by modulating enhancer-promoter interactions. The...

1996年12月15日 · Fab-7 deletions in the bithorax complex have a novel gain-of-function phenotype, typically transforming parasegment 11 (PS11) into PS12 identity. Genetic analysis indicates that removal of the Fab-7 element results in the fusion of the iab-6 (PS11) and iab-7 (PS12) cis-regulatory domains into a sing …

2012年3月28日 · Here, we have demonstrated that one of these three well studied insulators, Fab-7, is able to protect the yellow gene transcription from the most powerful Polycomb-dependent silencer from the bxd regulatory domain of the Ultrabithorax gene (Ubx). The barrier activity requires a region containing GAF-binding sites.