Thermolysin is the most stable member of a family of metalloproteinases produced by various Bacillus species. These enzymes are also termed 'neutral' proteinases or thermolysin -like …

2008年12月18日 · Some enzymes of the family are able to function at the extremes of temperatures, and some function in organic solvents. Thereby enzymes of the thermolysin …

Thermolysin from Bacillus thermoproteolyticus was the first metalloendopeptidase whose 3D structure was solved by X-ray crystallography (Matthews et al. 1972, 1974; Colman et al. …

Thermolysin is the name first given to an extracellular 34.6 kDa metalloendopeptidase secreted by the grampositive thermophilic bacterium Bacillus thermoproteolyticus (Endo, 1962). It was the …

Thermolysin Synonyms. 3.4.24.27; Thermostable neutral proteinase; Gene Name npr UniProtKB Entry P00800 Swiss-Prot Organism Bacillus thermoproteolyticus NCBI Taxonomy ID 1427 …

Thermolysin, a thermostable endopeptidase, is recognised as a potential peptide bond forming enzyme. The importance of structural properties and its stereospecific nature towards peptide …

The zinc endopeptidase thermolysin (EC 3.4.24.27), an extracellular enzyme from Bacillus thermoproteolyticus, is synthesized as a preproprotein, with the prosequence (204 residues) …

2023年12月17日 · (1988): Structural basis of the action of thermolysin and related zinc peptidases. In: Acc. Chem. Res. 21(9); 333–340; http://dx.doi.org/10.1021/ar00153a003; ↑ …

Thermolysin is a zinc metalloprotease enzyme belonging to the thermolysin family, with low substrate specificity. It plays a role in degrading antimicrobial peptides and cleaving …

The catalytic mechanism of thermolysin (type-example of the family) is probably the best studied of all metallopeptidases, but all details are not completely understood.