Thy-1 or CD90 (Cluster of Differentiation 90) is a 25–37 kDa heavily N-glycosylated, glycophosphatidylinositol (GPI) anchored conserved cell surface protein with a single V-like immunoglobulin domain, originally discovered as a thymocyte antigen. Thy-1 can be used as a marker for a variety of stem cells and for the axonal processes of mature ...

2024年12月25日 · THY1 (Thy-1 Cell Surface Antigen) is a Protein Coding gene. Diseases associated with THY1 include Retinal Artery Occlusion and Thymoma. Among its related pathways are Metabolism of proteins and Integrin Pathway. Gene Ontology (GO) annotations related to this gene include protein kinase binding and GTPase activator activity.

Thy-1, or CD90, is a glycophosphatidylinositol-linked glycoprotein expressed on the surface of neurons, thymocytes, subsets of fibroblasts, endothelial cells, mesangial cells and some hematopoietic cells. Thy-1 is evolutionarily conserved, ...

Thy-1 或 CD90（Cluster of Differentiation 90，分化簇90）是一个25-37kDa重度N-糖基化的细胞表面蛋白质，通过C-末端的糖磷脂酰肌醇（glycophosphatidylinositol，GPI）锚定到细胞膜外侧。CD90最初作为一个胸腺細胞的表面抗原发现，故最早称为Thy-1。

2006年10月1日 · Thy-1 is a 25–37 kDa glycosylphosphatidylinositol (GPI)-anchored protein involved in T cell activation, neurite outgrowth, apoptosis, tumor suppression, wound healing, and fibrosis. To mediate these diverse effects, Thy-1 participates in multiple signaling cascades.

Thy-1 细胞表面抗原： 该基因编码细胞表面糖蛋白和免疫球蛋白超家族的成员。 编码的蛋白质参与许多细胞类型的细胞粘附和细胞通讯，但特别是在免疫和神经系统的细胞中。

2004年9月15日 · Thy-1 (CD90) is a small GPI-anchored protein that is particularly abundant on the surface of mouse thymocytes and peripheral T cells. T cell proliferation and cytokine synthesis in response to Thy-1 cross-linking by specific mAb suggests a role for Thy-1 in mouse T lymphocyte activation.

2020年9月5日 · THY1 is a candidate tumour suppressor gene with decreased expression in metastatic nasopharyngeal carcinoma. Lung HL, et al. Oncogene, 2005 Sep 29. PMID 16007174. What's a GeneRIF?

Thy-1 is not a marker of oval cells but is present on a subpopulation of myofibroblasts/stellate cells. Thy-1/Thy-1 ligand interaction may play a role in adhesion of melanoma cells to endothelial cells; results indicate that alphaX-beta2 specifically interacts with Thy-1

Thy-1抗原(原称θ抗原)是小鼠T细胞的一个重要的表面抗原,同时又是区分小鼠T和B淋巴细胞的特异表面标记。 研究表明,Thy-1抗原还广泛地存在于包括人类在内的多种动物的脑及其他一些组织中。