Tiagabine, sold under the brand name Gabitril, is an anticonvulsant medication produced by Cephalon that is used in the treatment of epilepsy. The drug is also used off-label in the treatment of anxiety disorders including panic disorder.

噻 (sāi)加宾，又名替加宾，（英文名：Tiagabine），一种有机化合物。 化学式是C₂₀H₂₅NO₂S₂，分子量为375.55。 白色至类白色结晶性粉末，无臭。 熔点192℃ (分解)。 主要用作成人或儿童部分 癫痫 的辅助治疗剂。 为 γ-氨基丁酸 (GABA)吸收抑制剂。 用于12岁以下儿童及成人的癫痫治疗维持用药。 [1] 口服可以在体内几乎完全吸收，高脂餐会降低吸收速率。 人体内半衰期8小时左右。 噻加宾的生理作用是通过降低 中枢神经系统 的无序电活动而实现的。 可能引 …

Tiagabine is used to help control some types of seizures in the treatment of epilepsy. This medicine cannot cure epilepsy and will only work to control seizures for as long as you continue to take it. Tiagabine is available only with your doctor's prescription. This product is available in the following dosage forms:

Tiagabine is a piperidinemonocarboxylic acid that is (R)-nipecotic acid in which the hydrogen attached to the nitrogen has been replaced by a 1,1-bis (3-methyl-2-thienyl)but-1-en-4-yl group. A GABA reuptake inhibitor, it is used (generally as the hydrochloride salt) for the treatment of …

2005年6月13日 · Tiagabine is an antiepileptic used to treat partial seizures. Tiagabine is an anti-convulsive medication. It is also used in the treatment for panic disorder as are a few other anticonvulsants.

Tiagabine is used in combination with other medications to treat partial seizures (a type of epilepsy). Tiagabine is in a class of medications called anticonvulsants. It is not known exactly how tiagabine works, but it increases the amount of natural chemicals in the brain that prevent seizure activity. How should this medicine be used?

2025年2月10日 · Tiagabine is an anti-epileptic medication, also called an anticonvulsant. Tiagabine is used in combination with other medications to treat partial seizures in adults and children who are at least 12 years old. Tiagabine may also be used for purposes not listed in this medication guide.

Understanding the molecular basis of the B 0 AT2 inhibition by loratadine led to the discovery of a new inhibitor that is tiagabine, an anticonvulsant drug prescribed off-label in the treatment of anxiety and possessing antidepressant features.

Tiagabine (TGB) is a recently approved antiepileptic drug (AED) that inhibits y-aminobutyric acid (GABA) reuptake into neurons and glia, a mechanism of action that is specific and unique among the AEDs. TGB is potent and has linear and predictable pharmacokinetics.

本品一般作为辅助治疗，用于成人及12岁以上儿童难治性部分性癫痫发作。 片剂：（1）2mg：4mg。 （2）12mg：16mg。 初始剂量为12mg/d，分2次服用，每周可增加剂量12-24mg。 通常有效剂量为24-60mg/d，分2-4次服用。 肝功能不全患者须降低剂量。 1、不良反应可见困倦、头晕、头痛、疲乏、咽炎、呕吐、腹泻、易怒、注意力不集中。 2、少见有弱视、眼炎、肌无力、肌痛、失眠、精神紊乱、抑郁、瘙痒、共济失调、感觉障碍。 3、罕见有健忘、情绪 …