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2006年9月4日 · Several somatic mutations within the tyrosine kinase domain of epidermal growth factor receptor (EGFR) have been identified that predict clinical response of non-small-cell lung carcinoma (NSCLC)...

2011年8月8日 · Here, we report a new mechanism of EGFR-c-Src synergy through choline kinase α (CHKA). The first enzyme of the phosphatidyl choline production pathway, CHKA, is overexpressed in many cancers, and...

Cai W, Wu Y, Chen K, Cao Q, Tice DA, Chen X. In vitro and in vivo characterization of 64Cu-labeled AbegrinTM, a humanized monoclonal antibody against integrin avb3.

Biscardi JS, Maa MC, Tice DA, Cox ME, Leu TH, Parsons SJ. c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function.

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2023年12月27日 · 对于抗体药物偶联物（Antibody-Drug Conjugates，ADCs），抗体的内化是一种重要的作用机制，它可以促使ADCs从靶细胞质膜上的结合位点转移到溶酶体的裂解环境中，从而释放与其连接的毒素。 内化的效率直接影响着ADCs的治疗指数，因此需要提供一种方便、高效且易于使用的工具来研究抗体的内化过程和标记。 上期我们介绍了 基于生物毒素皂草素 (ZAP)二级偶联物的 抗体内化检测 方案： 抗体内化，抗体药物筛选经典方案（中文操作指南）

2020年1月9日 · A deusa Ticê foi considerada, dentro da mitologia tupi-guarani, a deusa do submundo. Diz a lenda que as pessoas a temiam muito pela grandiosidade de poder que ela …

2024年11月20日 · Associe-se ao TICE.PT e envolva-se nos desafios da economia digital! Associe-se Já! Para estar sempre a par das novidades.

" We 're having to create a whole new market , " said tice , acknowledging the challenge . “我们必须创建一个全新的市场，”泰斯承认这是一个巨大的挑战。 For tice , d.light 's successes are proof of prahalad 's thesis . 泰斯觉得，d.Light的成功证明了普哈拉的理论。 …