It is marketed under the trade name Tikosyn by Pfizer, and is available in the United States in capsules containing 125, 250, and 500 μg of dofetilide. It is not available in Europe [ 3 ] or Australia.

Medscape - Atrial fibrillation dosing for Tikosyn, (dofetilide), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost...

2025年2月6日 · Dofetilide is a class III antiarrhythmic agent primarily used to convert atrial fibrillation or atrial flutter to normal sinus rhythm and maintain sinus rhythm in patients with highly symptomatic atrial fibrillation or atrial flutter lasting longer than a week.

Sotalol (IV loading): You will have your blood drawn on arrival and have an ECG done. These results will inform your providers what dose of the medication needs to be given through your IV, and the bag of the medication will be ordered from the pharmacy. The bag of the medication will be infused intravenously (IV) over 1 hour.

Tikosyn was approved on October 1, 1999 for the maintenance of normal sinus rhythm (delay in time to recurrence of atrial fibrillation/atrial flutter) in patients with atrial fibrillation /atrial...

TIKOSYN is indicated for the maintenance of normal sinus rhythm (delay in time to recurrence of atrial fibrillation/atrial flutter [AF/AFl]) in patients with atrial fibrillation/atrial flutter of greater than one week duration who have been converted to normal sinus rhythm.

2023年8月23日 · Tikosyn is a prescription medicine that is used to treat an irregular heartbeat (atrial fibrillation or atrial flutter). It is not known if this medication is safe and effective in children under 18 years of age.

Dofetilide, a new class III antiarrhythmic agent, selectively blocks a specific cardiac potassium channel, IKr, increasing the effective refractory period of the myocyte and thereby terminating reentrant arrhythmias.

TIKOSYN® (dofetilide) medication page for healthcare professionals to search for scientific information on Pfizer medications. Also find the prescribing information, announcements, resources, and channels to connect with Pfizer Medical Information

2025年2月9日 · The dose of TIKOSYN must be individualized according to calculated creatinine clearance and QTc. (QT interval should be used if the heart rate is <60 beats per minute. There are no data on use of TIKOSYN when the heart rate is <50 beats per minute.)