
Tiratricol - Wikipedia
Tiratricol (also known as TRIAC or triiodothyroacetic acid) is a thyroid hormone analogue. Triiodothyroacetic acid is also a physiologic thyroid hormone that is present in the normal organism in low concentrations.
Tiratricol (Synonyms: 替拉曲可; 3,3',5-Triiodothyroacetic acid)
Tiratricol is an intracellular toxin neutralizer that inhibits LPS and lipid A cytotoxicity with IC 50 s of 20 μM and 32 μM, respectively. Tiratricol reduces TNF production in lipopolysaccharide-stimulated macrophages. Tiratricol also has antiviral activity and is an inhibitor of yellow fever virus . It can bind to the RdRp domain of the ...
替拉曲可 - 维基百科,自由的百科全书
替拉曲可,英文:Tiratricol (也称为:替拉曲考,TRIAC或三碘甲状腺乙酸),是一种甲状腺激素 类似物。 三碘甲状腺乙酸也是一种生理性 甲状腺激素 ,它以低浓度存在于正常生物体中。
Emcitate | European Medicines Agency (EMA)
Emcitate is a medicine used to treat peripheral thyrotoxicosis (excess blood levels of certain thyroid hormones) in people with monocarboxylate transporter 8 (MCT8) deficiency. MCT8 deficiency is also known as Allan-Hernon-Dudley syndrome, …
替拉曲可 (Tiratricol) - 药物靶点:THR-α x THR-β_在研适应 …
Tiratricol与甲状腺受体具有高亲和力结合,不需要 MCT8 进入细胞。 它发挥与T3相似的生物学效应,可以恢复MCT8依赖性组织中的正常甲状腺激素活性(图7)。
Tiratricol: Uses, Interactions, Mechanism of Action - DrugBank …
2005年6月13日 · A metabolite of T3 and T4 thyroid hormones; promoted for hyperlipidemia, localized lipodystrophy, and obesity. Tiratricol has been used in trials studying the treatment of Allan-Herndon-Dudley Syndrome.
TIRATRICOL - Uses, Side Effects, and More - WebMD
Tiratricol is a thyroid hormone that occurs naturally in the body. It can also be made in a lab and taken by mouth under the supervision of a healthcare provider. Tiratricol can alter thyroid...
Tiratricol: Health Benefits, Side Effects, Uses, Dose ... - RxList
Tiratricol is used as a dietary supplement for thyroid problems including thyroid cancer. It is also used for increasing metabolic rate for weight loss, and reducing cellulite.
Tiratricol - an overview | ScienceDirect Topics
Tiratricol is an active derivative of the thyroid hormone triiodothyronine (T3) and has been used as a T 3 analogue in the treatment of thyroid hormone resistance syndromes (13). Tiratricol has enhanced hepatic and skeletal thyromimetic effects in comparison with thyroxine (T4) (14).
Tiratricol | C14H9I3O4 | CID 5803 - PubChem
Tiratricol is a metabolite of T4. Tiratricol is indicated in the management of thyroid hormone resistance syndrome and is used, in combination with levothyroxine, to suppress thyroid-stimulating hormone production in patients with thyroid …