2020年7月28日 · Total metabolic tumor volume (TMTV) is a promising quantitative biomarker for therapy assessment and prognosis in Hodgkin Lymphoma affected patients that allows...

TMTV-Net demonstrates robust performance and adaptability in TMTV segmentation across diverse multi-site external datasets, encompassing various lymphoma subtypes. Furthermore, we have containerized our model and made it available in this repository for additional multi-site evaluations and generalizability analyses.

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2024年2月8日 · Total metabolic tumor volume (TMTV) segmentation has significant value enabling quantitative imaging biomarkers for lymphoma management. In this work, we tackle the challenging task of automated tumor delineation in lymphoma from PET/CT scans using a cascaded approach. Our study included 1418 2-[18F]FDG …

• Total metabolic tumor volume (TMTV) is a quantitative radiological assessment of total tumor burden that can be derived from 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) scans.1 • Although the TMTV metric has prognostic value in diffuse large B-cell lymphoma (DLBCL)2,3

2022年2月6日 · This generic deep learning model to compute TMTV in lymphomas can drastically reduce computation time of TMTV. The total metabolic tumor volume (TMTV) is a new prognostic factor in lymphomas that could benefit from automation with deep learning convolutional neural networks (CNN).

2024年9月3日 · Total metabolic tumor volume (TMTV) is prognostic in lymphoma. However, cutoff values for risk stratification vary markedly, according to the tumor delineation method used. We aimed to create a standardized TMTV benchmark dataset allowing TMTV to be tested and applied as a reproducible biomarker.

2024年11月5日 · Total metabolic tumor volume (TMTV) derived from positron emission tomography/computed tomography (PET/CT) data has been shown to serve as an accurate tumor burden surrogate and be associated with outcomes in FL (Cottereau et al. Ann Oncol 2024).

Our model, TMTV-Net, is specifically designed to automate TMTV segmentation from PET/CT scans. TMTV-Net demonstrates robust performance and adaptability in TMTV segmentation across diverse multi-site external datasets, encompassing various lymphoma subtypes.

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