In this study, we focused on the prognostic value of PET/CT-derived tumor metabolic, clinical, and biological parameters in risk stratification of DLBCL before treatment. We found that BVG, TLG, TMTV, and Ki-67 were found to be independent prognostic …

2024年1月3日 · Our findings suggest that BVG, TLG, TMTV, and Ki-67 are independent prognostic indicators for survival in patients with pre-treatment DLBCL, especially BVG, which is a novel prognostic indicator that has to be validated in future research.

This repository employs a deep-learning method for the automated segmentation of total metabolic tumor volume (TMTV) in whole-body [18]F-FDG PET/CT images, with an emphasis on multi-center generali...

2024年12月16日 · We aimed to explore the predictive value of total metabolic tumor volume (TMTV) and beta-2-microglobulin (B2M) levels in patients with follicular lymphoma (FL) with a high tumor burden receiving standard first-line immunochemotherapy.

基线肿瘤代谢指标包括最大葡萄糖标准摄取值（SUVmax）、平均摄取值（SUVmean）、总肿瘤代谢体积（TMTV）、总糖酵解率（TLG）。 分析肿瘤代谢参数及临床和血液学相关指标对治疗的影响。 结果 51例患者中，20例复发或进展，中位无进展生存（PFS）期时间为12.0个月（1.0~64.0个月），2年PFS率为25.5%（13/51）。 TMTV、TLG与血清乳酸脱氢酶（LDH）水平的相关性较强。 单因素分析显示Ann Arbor分期、NCCN-IPI评分、TMTV均对预后有显著相关 …

2024年2月8日 · Total metabolic tumor volume (TMTV) segmentation has significant value enabling quantitative imaging biomarkers for lymphoma management. In this work, we tackle the challenging task of automated tumor delineation in lymphoma from PET/CT scans using a cascaded approach. Our study included 1418 2-[18F]FDG …

2021年12月1日 · Baseline TMTV appears to be a useful independent prognostic factor for predicting relapse in advanced-stage HL in ABVD subgroup, with a tendency of survival curves separation in BEACOPP subgroup.

2025年3月3日 · This study aimed to evaluate the prognostic value of 18F-FDG PET/CT parameters including maximum standardized uptake value (SUVmax), total metabolic tumor volume (TMTV) and total lesion glycolysis (TLG), and to develop a …

2024年1月17日 · Our study demonstrates that the integration of TMTV on baseline 18 F-FDG PET/CT with EGFR mutation status improves the accuracy of prognostic evaluation for patients with LUAD.

High baseline TMTV (±ECOG) was a strong prognosticator of inferior PFS and OS in REMARC patients post-R-CHOP, irrespective of maintenance. Early identification of ultra-risk diffuse large B-cell lymphoma (DLBCL) patients is needed to aid stratification to innovative treatment.