Mar 30, 2025 · TNFSF14 (TNF Superfamily Member 14) is a Protein Coding gene. Diseases associated with TNFSF14 include Graft-Versus-Host Disease and Cicatricial Entropion. Among its related pathways are MIF Mediated Glucocorticoid Regulation and ERK Signaling.

May 15, 2020 · Tumor necrosis factor superfamily member 14 (LIGHT) has been in pre-clinical development for over a decade and shows promise as a modality of enhancing treatment approaches in the field of cancer immunotherapy.

May 14, 2020 · Tumor necrosis factor superfamily member 14 (LIGHT) has been in pre-clinical development for over a decade and shows promise as a modality of enhancing treatment approaches in the field of cancer immunotherapy.

TNFSF14, a novel target of miR-326, facilitates airway remodeling in airway smooth muscle cells via inducing extracellular matrix protein deposition and proliferation. The impact of TNFSF14 on prognosis and immune microenvironment in clear cell renal cell carcinoma.

Sep 6, 2023 · Du and colleagues established novel LIGHT/TNFSF14-secreting CAR-T cells that have significantly enhanced trafficking, cytotoxicity, and clinical potential to solid tumors through reconstituting normalized tumor vasculature and tertiary lymphoid structures (TLSs) in the tumor microenvironment.

Dec 31, 2015 · Here we identify the cytokine tumor necrosis factor superfamily member 14 (Tnfsf14) as a positive regulator of myoblast differentiation in culture and muscle regeneration in vivo.

Apr 20, 2020 · LIGHT, also known as tumor-necrosis factor (TNF) superfamily member 14 (TNFSF14), is predominantly expressed on activated immune cells and some tumor cells. LIGHT is a pivotal regulator both for...

TNFRSF14 (Herpes virus entry mediator A, 283aa) is a receptor for BTLA, TNFSF14 /LIGHT and homotrimeric TNFSF1, is involved in lymphocyte activation and plays an important role in HSV pathogenesis. See Table T1 .

Feb 8, 2025 · LIGHT/TNFSF14 promotes CAR-T cell trafficking and cytotoxicity through reversing immunosuppressive tumor microenvironment. Tumor Necrosis Factor Superfamily 14 (LIGHT) Restricts Neovascularization by Decreasing Circulating Endothelial Progenitor Cells and Function.

Mar 5, 2024 · This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus.