
Vascular endothelial growth inhibitor - Wikipedia
Vascular endothelial growth inhibitor (VEGI), also known as TNF-like ligand 1A (TL1A) and TNF superfamily member 15 (TNFSF15), is protein that in humans is encoded by the TNFSF15 …
TNFSF15 Gene - GeneCards | TNF15 Protein | TNF15 Antibody
2024年12月25日 · TNFSF15 (TNF Superfamily Member 15) is a Protein Coding gene. Diseases associated with TNFSF15 include Primary Biliary Cholangitis and Diverticulitis. Among its …
TNFSF15/TL1A:药企巨头抢滩布局,下一个百亿级靶点的崛起之 …
TNFSF15,即肿瘤坏死因子超家族成员15,又名TL1A,为Ⅱ型跨膜蛋白,由胞内区、跨膜区和胞外区构成。 其中,胞外区含有保守的TNF同源结构域,这一结构域是TNFSF15与受体结合的 …
TNF 超家族成员 15(TNFSF15)基因 | MCE - MCE-生物活性 ...
这种细胞因子是受体 TNFRSF25 和诱饵受体 TNFRSF21/DR6 的配体。 它可以激活 NF-kappaB 和 MAP 激酶,并作为自分泌因子诱导内皮细胞凋亡。 还发现这种细胞因子可抑制内皮细胞增殖, …
TL1A/TNFSF15 directly induces proinflammatory cytokines
2012年12月19日 · Tumor necrosis factor (TNF)-like cytokine 1A (TL1A)/TNF superfamily member 15 (TNFSF15) is a proinflammatory cytokine and TNFα superfamily member that is linked...
TNFSF15 TNF superfamily member 15 [ (human)] - National …
TNFSF15 is an ethnic-specific IBD susceptibility gene. Five SNPs that comprise the 2 common haplotypes were genotyped in 599 Caucasian patients with Crohn's dis, 382 Caucasian …
A stable, engineered TL1A ligand co-stimulates T cells via ... - Nature
2022年11月29日 · TL1A (TNFSF15) is a TNF superfamily ligand which can bind the TNFRSF member death receptor 3 (DR3) on T cells and the soluble decoy receptor DcR3. Engagement …
TNFSF15 TNF superfamily member 15 [ Homo sapiens (human) ]
2025年2月8日 · Title: Genome-wide association study identifies TNFSF15 associated with childhood asthma. Nonylphenol regulates TL1A through the AhR/HDAC2/HNF4alpha pathway …
TNFSF15- 信号通路|蛋白抗体-华美生物
TNFSF15主要作为死亡受体3(DR3)的配体,参与调控VEGF/VEGFR信号通路,影响内皮细胞的增殖、凋亡以及淋巴管生成等过程。 它在血管生成、淋巴管形成、免疫调节等多个方面发挥 …
TNFSF15 Promotes Antimicrobial Pathways in Human Macrophages ... - PubMed
We identify that autocrine/paracrine TNFSF15 is required for optimal PRR-enhanced antimicrobial pathways in macrophages, define mechanisms regulating TNFSF15-dependent bacterial …