Tofacitinib is available in the form of a tablet (Xeljanz), an extended release tablet (Xeljanz XR) and as an oral solution. It is used to treat certain inflammatory conditions in people who have already tried tumor necrosis factor (TNF) blockers.

2024年7月1日 · Find patient medical information for Xeljanz (tofacitinib) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings

2023年6月13日 · Tofacitinib is used in the treatment of rheumatoid arthritis. Tofacitinib is an Janus kinase inhibitor. It works by blocking the action of the enzyme, Janus kinase. This decreases inflammation and joint damage in rheumatoid arthritis.

6 天之前 · Adults—5 milligrams (mg) 2 times a day together with another medicine. Your doctor may adjust your dose as needed. Children—Use and dose must be determined by your doctor. For ulcerative colitis: For oral dosage form (extended-release tablets): Adults—22 milligrams (mg) once a day for at least 8 weeks, then 11 mg once a day.

2024年4月17日 · Learn about the side effects of tofacitinib, from common to rare, for consumers and healthcare professionals.

2024年9月11日 · If taking 5 mg orally twice a day: Dose should be reduced to 5 mg orally once a day. Extended-release tablets: If taking 22 mg orally once a day: Dose should be reduced to 11 mg orally once a day.

Tofacitinib is used alone or with other medications to treat rheumatoid arthritis (condition in which the body attacks its own joints causing pain, swelling, and loss of function) in adults who are unable to take or did not respond to one or more tumor necrosis factor (TNF) inhibitor medication (s).

XELJANZ/XELJANZ XR is indicated for the treatment of adult patients with moderately to severely active rheumatoid arthritis who have had an inadequate response or intolerance to methotrexate....

Dosing and Monitoring XELJANZ 5 mg twice daily XELJANZ XR. 11 mg once daily. RA, PsA, and AS. pcJIA. Tab Number 3. Tab Number 4. Tab Number 5. Dosing and Administration Recommendations for RA, PsA, and AS 1 Use of XELJANZ/XELJANZ XR in patients with severe hepatic impairment is not recommended. 1. Changes between XELJANZ and XELJANZ XR …

XELJANZ is a Janus kinase (JAK) inhibitor that helps regulate an overactive immune system. It helps disrupt JAK pathways from inside the cells, which are believed to play a role in inflammation. Take an active role in your treatment with …