Purpose: The association of methadone with Q-T interval prolongation and torsades de pointes (TdP) is reviewed, and recommendations for preventing Q-T interval prolongation in methadone users are ...

Table 1. Summary of cases of long-QT, torsades de pointes and cardiac arrest in the presence of clarithromycin. Case Max QTc Clarithromycin dose Other QT prolongers Female gender K Mg Bradycardia ...

2001年3月14日 · A study comparing the incidence of drug-related torsade de pointes in patients receiving dofetilide or placebo indicates that pause-dependent polymorphic ventricular tachycardia may be more common ...

Cite this: Methadone-associated Q-T Interval Prolongation and Torsades de Pointes - Medscape - May 01, 2009. Abstract and Introduction Risk Factors Associated With Q-T Interval Prolongation and TdP

The presented case highlights the development of TdP and cardiac arrest in the setting of a prolonged QT interval following treatment with clarithromycin. Several risk factors for LQTS were ...

2024年3月21日 · Broader validation over an unselected general population may support broad application of this model to stratify torsade de pointes risk in patients with suspected long QT syndrome. The ...

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2002年9月18日 · In patients taking very high doses of methadone, 17 cases of torsades de pointes have been reported. (Krantz MJ et al. Ann Intern Med 2002;137:501-504. Sep 18, 2002

2013年3月12日 · The macrolide-class antibiotic can cause abnormal changes in the electrical activity of the heart that may prolong the QT interval and trigger a rare, associated arrhythmia called torsades de pointes.

2010年2月9日 · Hospitalized patients can be at increased risk of sudden death associated with torsades de pointes, a polymorphic VT that can be a side effect of certain drugs and promoted by a number of genetic ...