IRF7: activation, regulation, modification and function
2011年4月14日 · Interferon regulatory factor 7 (IRF7) was originally identified in the context of Epstein–Barr virus (EBV) infection, and has since emerged as the crucial regulator of...
Identification of splenic IRF7 as a nanotherapy target for tele ...
2025年2月24日 · Single-cell RNA-seq analysis identifies IRF7 as a pivotal mediator in the spleen-heart communication network that is initially induced in the spleen and orchestrates functional …
IRF7: role and regulation in immunity and autoimmunity
2023年8月9日 · Interferon regulatory factor (IRF) 7 was originally identified as master transcriptional factor that produced IFN-I and regulated innate immune response, subsequent …
IRF7 Gene - GeneCards | IRF7 Protein | IRF7 Antibody
2024年12月25日 · IRF7 (Interferon Regulatory Factor 7) is a Protein Coding gene. Diseases associated with IRF7 include Immunodeficiency 39 and Primary Immunodeficiency With …
IRF-7 is the master regulator of type-I interferon-dependent
2005年3月30日 · Using mice deficient in the Irf7 gene (Irf7-/- mice), we show that the transcription factor IRF-7 is essential for the induction of IFN-α/β genes via the virus-activated, MyD88 …
Interferon regulatory factor 7 in inflammation, cancer and infection
2023年5月11日 · Interferon regulatory factor 7 (IRF7), a member of the interferon regulatory factors (IRFs) family, is located downstream of the pattern recognition receptors (PRRs) …
Transcriptional repression of IRF7 by MYC is critical for type I ...
We demonstrate that transcriptional repression of IRF7 by MYC provides an additional layer of tight regulation of IRF7 that ensures the appropriate level of type I IFN production and …
IRF7：在免疫和自身免疫中的作用和调节,Frontiers in Immunology
干扰素调节因子（IRF）7最初被认为是产生IFN-I并调节先天免疫反应的主要转录因子，随后的研究表明IRF7在多种生物过程中发挥多方面和多功能的功能。 在这篇综述中，我们全面概述了 …
IRF7 interferon regulatory factor 7 - NIH Genetic Testing …
2024年6月17日 · This gene encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. It has been shown to play a role in the …
Potentiation and tolerance of toll-like receptor priming in human ...
We found as with previous experiments, the priming of Poly I:C induced significant enhancement of total IRF7, while neither LPS nor Pam3Csk4 priming had any notable effect on IRF7 …
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