2013年2月6日 · Our data show that TRAK1 binds to both kinesin-1/KIF5B and dynein/dynactin and steers mitochondria into axons, whereas TRAK2 predominantly interacts with …

2020年6月19日 · Here, we demonstrate that TRAK1 (Milton), an adaptor protein essential for mitochondrial trafficking, activates kinesin-1 and increases robustness of kinesin-1 stepping on …

2023年5月22日 · The IL-4 and/or IL-13-induced stimulation of the STAT6 pathway triggers M2 macrophage activation. 58,59 arginase-1 (Arg-1), out of frequent markers for M2 macrophage, …

2025年2月4日 · We first show that macrophages actively take up human heavy chain ferritin (HFt) in vitro via macrophage scavenger receptor 1 (MSR1). We further manifest that drug-loaded …

Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to …

2025年3月30日 · TRAK1 (Trafficking Kinesin Protein 1) is a Protein Coding gene. Diseases associated with TRAK1 include Developmental And Epileptic Encephalopathy 68 and Non …

2023年9月21日 · Results: TRAIL increased the expression of M1 markers at both mRNA and protein levels while decreasing the expression of M2 markers at the mRNA level in human …

2018年5月26日 · TRAK1 is a kinesin adaptor protein that has several putative roles. Gilbert et al. (2006) described a hypertonic mouse model with mutated Trak1. These mice had lower GABA …

2013年5月2日 · A murine model of GR interacting protein 1–deficient macrophages exhibits impaired repression of NFκB target genes. Furthermore, systemic challenge with LPS resulted …

2021年10月1日 · Irf1- regulated 90 molecules contribute to the inflammation and viral defense. Egr1- regulated 116 molecules contribute to anti-inflammation and proliferation. Macrophage …