2025年1月1日 · Trazodone is an antidepressant that belongs to a group of drugs called serotonin receptor antagonists and reuptake inhibitors (SARIs). While trazodone is not a true member of the selective serotonin reuptake inhibitors (SSRIs) class of antidepressants, it does still share many properties of the SSRIs.

5 天之前 · Trazodone is also an antagonist at several other monoaminergic receptors including 5-HT2B (Ki = 78.4 nM), 5-HT2C (Ki = 224 nM), α1A (Ki = 153 nM), α2C (Ki =155 nM) receptors and it is a partial agonist at 5-HT1A (Ki = 118 nM) receptor. Trazodone antagonizes alpha 1-adrenergic receptors, a property which may be associated with postural ...

2024年3月18日 · Substantially increased plasma trazodone concentrations possible, with potential for adverse effects. If used concomitantly, consider reduction in trazodone dosage. MAO inhibitors. Limited experience. Initiate trazodone therapy cautiously if MAO inhibitors are discontinued shortly before or are to be given concomitantly with trazodone. Nefazodone

2024年9月11日 · Trazodone has a unique chemical structure and is unrelated to selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants (TCAs), or monoamine oxidase inhibitors (MAO inhibitors). It is structurally related to nefazodone. Trazodone and nefazodone belong to the class of drugs known as serotonin modulators.

Trazodone (Ingredient) Chemical formula: C19H22ClN5O Drugbank ID: DB00656 ATC code: N06AX05. The information below refers to products available in the United States that contain trazodone. Products containing trazodone trazodone systemic. Brand names: Desyrel, Oleptro, Desyrel Dividose, Raldesy Drug class: phenylpiperazine antidepressants

Phenylpiperazine antidepressants are drugs that act as serotonin (5-HT2) reuptake inhibitors and serotonin receptor blockers, or just as serotonin receptor blockers. There are two drugs in this class of antidepressants and their mechanism of action …

2024年8月22日 · The U.S. Food and Drug Administration (FDA) does not recognize trazodone as a controlled substance because studies have not shown that people who take trazodone are likely to start abusing the drug. A controlled substance is an illegal or prescription drug deemed addictive or inclined to result in drug abuse and dependency.

2023年8月10日 · More about Desyrel (trazodone) Check interactions; Compare alternatives; Reviews (39) Drug images; Latest FDA alerts (3) Side effects; Dosage information; During pregnancy; Drug class: phenylpiperazine antidepressants; Breastfeeding; Patient resources. Desyrel advanced reading; Other brands. Oleptro, Desyrel Dividose. Professional resources ...

2024年2月3日 · Do not start, stop, or change the dose of any drug without checking with your doctor. What are some things I need to know or do while I take Trazodone Extended-Release Tablets? Tell all of your health care providers that you take this medicine (trazodone extended-release tablets). This includes your doctors, nurses, pharmacists, and dentists.

Trazodone Interactions. There are 654 drugs known to interact with trazodone, along with 8 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 138 are major, 501 are moderate, and 15 are minor.