TRK-750，由Toray Industries, Inc. (Toray Industries, Inc.)公司最早进行研发，目前全球最高研发状态为终止，治疗领域: 肿瘤,神经系统疾病,消化系统疾病。

2020年2月17日 · 一项评估 TRK-750 在接受含奥沙利铂化疗后伴有化疗诱发周围神经病变的结直肠癌患者中的安全性、耐受性、药代动力学和药效学的研究. 该研究的主要目标是： • 评估多次口服（每天两次 [BID]）剂量的TRK-750 在接受奥沙利铂治疗并伴有化疗引起的周围神经病变 (CIPN) 的结直肠癌患者中的安全性和耐受性。 该研究的次要目标是： 评估多次口服 (BID) 剂量的 TRK-750 在减少奥沙利铂治疗的 CIPN 结直肠癌患者的神经性症状、改善生活质量 (QoL) 和临床医生报 …

2020年4月24日 · This crossover randomized study is aimed at investigating the safety, tolerability, pharmacokinetics, and pharmacodynamics of TRK-750 (Toray Industries, Inc, Chuo-ku, Tokyo, Japan in colorectal cancer patients following OHP containing chemotherapy in the adjuvant setting and developing chronic OIPN.

This is a Phase II, randomised, double-blind, placebo controlled, crossover study conducted at multiple study sites to assess the safety, tolerability, pharmacokinetic (PK), and efficacy of multiple oral (BID) doses of TRK-750 in colorectal cancer patients with Chemotherapy induced Peripheral Neuropathy (CIPN).

2023年1月6日 · TRK 750, an orally available compound is being developed by Toray, for the treatment of peripheral neuropathic pain. Phase II development was underway in the

La fat bike elettrica TRK 750x di Algi Ebikes rappresenta l'apice della tecnologia e del design nel settore delle e-bike. Progettata per gli appassionati di avventure off-road e per chi cerca il massimo del comfort e delle prestazioni, la TRK 750x offre un'esperienza di guida indimenticabile.

2025年1月23日 · The primary objective of the study is: • to assess the safety and tolerability of multiple oral (twice daily [BID]) doses of TRK-750 in oxaliplatin-treated colorectal cancer patients with chemotherapy-induced peripheral neuropathy (CIPN).

An Exploratory, Randomised, Double-blind, Placebo-controlled, Phase I Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Food-effect of TRK-750 in Healthy Adults and Patients With Peripheral Neuropathic Pain

TRK-750 is being developed by Toray Industries for the treatment of patients with Chemotherapy-induced Peripheral Neuropathy. (Sourced from: https://clinicaltrials.gov/ct2/show/NCT04282590?term=TRK-750&draw=2&rank=1)

2017年11月8日 · 一项探索性、随机、双盲、安慰剂对照的 i 期研究，以评估 trk-750 在健康成人和周围神经性疼痛患者中的安全性、耐受性、药代动力学、药效学和食物效应