The TSHR gene provides instructions for making a protein, known as a receptor, that attaches (binds) to a hormone called thyroid stimulating hormone (TSH). Learn about this gene and related health conditions.

Jul 24, 2017 · The thyroid-stimulating hormone (TSH) receptor (TSHR) is a member of the glycoprotein hormone receptors (GPHRs), a sub-group of class A G protein-coupled receptors (GPCRs). TSHR and its ligand thyrotropin are of essential importance for growth and function of the thyroid gland.

Dec 25, 2024 · TSHR (Thyroid Stimulating Hormone Receptor) is a Protein Coding gene. Diseases associated with TSHR include Hyperthyroidism, Familial Gestational and Hypothyroidism, Congenital, Nongoitrous, 1. Among its related pathways are Class A/1 (Rhodopsin-like receptors) and GPCR downstream signalling.

EST Analytical is a manufacturing leader of high quality GC sample preparation and analytical equipment. Purge and Trap Systems, SPME, Headspace.

Data indicate the structural integrity of thyroid stimulating hormone receptor isoform (TSHR) and its potential binding of thyroid stimulating hormone (TSH). TSHR protein was detected on human EOM myoblasts and increasing TSHR expression during myogenic differentiation.

The thyroid stimulating hormone receptor (TSHR) mutation database was established in 1999 and updated in 2018. It contains all published TSHR mutations identified in humans and their clinical characterizations. The TSHR is a G-protein coupled receptor with two major pathways.

Thyroid stimulating hormone receptor (TSHR) plays a pivotal role in thyroid hormone metabolism. It is a major controller of thyroid cell function and growth. Mutations in TSHR may lead to several thyroid diseases, most commonly hyperthyroidism.

Apr 13, 2022 · The TSH receptor (TSHR) is a member of the glycoprotein hormone receptors, a subfamily of family A G protein-coupled receptors. The TSHR is of great importance for the growth and function of the thyroid gland. The TSHR and its endogenous ligand TSH ...

Several TSHR gene mutations have been identified in people with congenital hypothyroidism, a condition characterized by abnormally low levels of thyroid hormones starting from birth.

The TSHR and its endogenous ligand TSH are pivotal proteins with respect to a variety of physiological functions and malfunctions. The molecular events of TSHR regulation can be summarized as a process of signal transduction, including signal reception, conversion, and …