Image & Title Alomone Labs TTA-P2 inhibits T-type Ca V channels in AZF cells. Bovine adrenal zona fasciculate (AZF) whole cell recordings. Ca 2+ currents were recorded in 10 mM Ba 2+ in …

TTA-P2 (T-Type calcium channel inhibitor) 是一种有效的 T 型钙通道抑制剂。TTA-P2 可很好地穿透 CNS 并阻断小脑深部核神经元中的天然 T 型电流，对于野生型和突变型 Cav3.1 通道，窗 …

T-type calcium channel inhibitorCalcium Channel Neurological Disease; TTA-P2 (T-Type calcium channel inhibitor) 是一种有效的 T 型钙通道抑制剂。TTA-P2 可很好地穿透 CNS 并阻断小脑深 …

作者：Melanie R. Grably博士 编码T型CaV离子通道的基因产生三个成孔亚基：CaV3.1、CaV3.2和CaV3.3，产生的电流在药理学和电生理学上不同于高压CaV1和CaV2通道电流。由 …

Genes encoding T-type Ca V channels yield three pore-forming subunits: Ca V 3.1, Ca V 3.2 and Ca V 3.3 which give rise to currents that are pharmacologically and electrophysiologically …

TTA-P2 (T-Type calcium channel inhibitor) is a potent inhibitor of T-Type calcium channel. TTA-P2 penetrates well the CNS and blocks the native T-type currents in deep cerebellar nuclear …

Several agents that are preferential T-type calcium (T-channel) blockers have shown promise as being effective in alleviating acute and chronic pain, suggesting an urgent need to identify …

Modulator No. 27 2019 www.alomone.com 13 Figure 1. T-Type Ca V Channel Inhibition by TTA-P2 in AZF Cells A. Bovine adrenal zona fasciculate (AZF) whole cell recordings. Ca 2+ …

Spinal cord injury (SCI)-induced neuropathic pain (SCI-NP) develops in up to 60 to 70% of people affected by traumatic SCI, leading to a major decline in quality of life and increased risk for …

TTA-P2 is a selective T-type calcium channel blocker. We investigated the role of the neurotrophin BDNF signalling via the TrkB receptor in rat adrenomedullary chromaffin cells …