2020年8月13日 · In this article, we present 4 patient cases that illustrate both common and complex clinical scenarios. We first present a review of erythropoiesis and then describe our approach to cancer-associated anemia by identifying the contributing causes before selecting specific treatments.

Microenvironmental M1 tumor-associated macrophage polarization influences cancer-related anemia in advanced ovarian cancer: key role of Interleukin-6. Haematologica 10.3324/haematol.2018.191551 [Epub ahead of print].

2021年3月11日 · Microangiopathic hemolytic anemia (MAHA) refers to a subgroup of hemolytic anemia where there is fragmentation and hemolysis due to damage of erythrocytes in the small blood vessels. It is characterized by the presence of …

2021年9月8日 · We demonstrate that reduced red blood cell (RBC) survival rather than altered erythropoiesis is driving the development of anemia. The tumor-induced inflammatory and metabolic remodeling affect RBC integrity and augment splenic phagocyte activity promoting erythrophagocytosis.

2021年9月10日 · We demonstrate that reduced red blood cell (RBC) survival rather than altered erythropoiesis is driving the development of anemia. The tumor-induced inflammatory and metabolic remodeling affect RBC integrity and augment splenic phagocyte activity promoting erythrophagocytosis.

There are several causes of cancer-associated malignant anemia, such as bleeding, hemolysis, lack of nutrition, bone marrow necrosis and fibrosis caused by tumor cell infiltration, direct inhibition of red blood cells caused by radiotherapy and chemotherapy, relative insufficiency of erythropoietin (EPO) secretion , hematopoietic inhibition and ...

2020年8月13日 · In this article, we present 4 patient cases that illustrate both common and complex clinical scenarios. We first present a review of erythropoiesis and then describe our approach to cancer-associated anemia by identifying the contributing causes before selecting specific treatments.

Cancer-associated anemia (CAA) is a major problem that remains largely unrecognized and therefore poorly managed. Almost 75% of all cancer patients will be found to have anemia during the course of their illness (hematological malignancies more than solid tumors).

2020年8月13日 · In this article, we present 4 patient cases that illustrate both common and complex clinical scenarios. We first present a review of erythropoiesis and then describe our approach to cancer-associated anemia by identifying the contributing causes before selecting specific treatments.

2021年9月8日 · Exercise might ameliorate tumor-associated anemia by reducing blood lactate and IL-1β. As exercise does not only normalize the lipid profile in blood but also elicits a variety of systemic effects such as an anti-inflammatory response, we assessed IL-1β levels in the plasma.