The type III secretion system (T3SS or TTSS) is one of the bacterial secretion systems used by bacteria to secrete their effector proteins into the host's cells to promote virulence and colonisation.

Type III secretion systems (T3SSs) are complex bacterial structures that provide gram-negative pathogens with a unique virulence mechanism enabling them to inject bacterial effector proteins directly into the host cell cytoplasm, bypassing the extracellular milieu.

Type III secretion systems (T3SS) afford gram-negative bacteria a most intimate means of altering the biology of their eukaryotic hosts — the direct delivery of effector proteins from the bacterial cytoplasm to that of the eukaryote.

2017年4月10日 · Type III secretion systems (T3SSs) are protein transport nanomachines that are found in Gram-negative bacterial pathogens and symbionts.

The non-flagellar type 3 protein secretion system (NF-T3SS), often named injectisome, is homologous to the flagellum and also acts as a T3SS. This system is used to secrete its extracellular components and to deliver effectors into host cells.

The type III secretion system (T3SS) delivers effector proteins into host cells through a needle-like apparatus that spans bacterial envelope, whereby mediating the bacterial invasion of host cells. Salmonella contains two T3SS encoded on Salmonella pathogenicity islands (SPI) 1 and 2.

2014年9月8日 · The type III secretion system (T3SS) is a membrane-embedded nanomachine found in several Gram-negative bacteria. Upon contact between bacteria and host cells, the syringe-like T3SS transfers proteins termed effectors from the bacterial cytosol to the cytoplasm or the plasma membrane of a single target cell. This is a major difference from ...

2025年2月8日 · The Type 3 Secretion System (T3SS) is a bacterial mechanism for transferring proteins directly from bacteria to host cells. This system is crucial in bacterial pathogenesis and survival, making it a significant focus in infectious disease research.

Type III secretion (T3S) systems are found in a large number of gram-negative bacteria where they function to manipulate the biology of infected hosts. Hosts targeted by T3S systems are widely distributed in nature and are represented by animals and plants.

2014年9月8日 · The type III secretion system (T3SS) is a membrane-embedded nanomachine found in several Gram-negative bacteria. Upon contact between bacteria and host cells, the syringe-like T3SS (Figure 1) transfers proteins termed effectors from the bacterial cytosol to the cytoplasm or the plasma membrane of a …