泛素羧基端酯酶L1（UCHL1）|ELISA指标 - 知乎 - 知乎专栏
UCH-L1 (Ubiquitin C-terminal hydrolase-L1)又称 PGP 9.5,是一种重要的泛素蛋白酶，广泛分布于大脑神经元和其他神经组织中。它是泛素底物的水解酶，能够参与到调节细胞内泛素化过程 …
Ubiquitin C-terminal hydrolase L1 (UCH-L1): structure, …
UCH-L1 is not essential for neuronal development but it is absolutely required for the maintenance of axonal integrity and UCH-L1 dysfunction is implicated in neurodegenerative disease. Here …
Ubiquitin carboxy-terminal hydrolase L1 - Wikipedia
Ubiquitin carboxy-terminal hydrolase L1 (EC 3.1.2.15, ubiquitin C-terminal hydrolase, UCH-L1) is a deubiquitinating enzyme. Neurons from rat brain tissue stained green with antibody to …
Science︱新启示! 阿尔茨海默病突触损伤的新机制, 提示S-亚硝基化 …
Uch-L1，全称泛素羧基末端水解酶L1，是一种去泛素化酶，水解泛素羧基末端加合成分，产生泛素单体【7】。为了方便，UCH-L1的S-亚硝基化，或S-亚硝基化的Uch-L1，统简称为SNO-Uch …
泛素羧基末端水解酶 L1 (UCH-L1) | 重组蛋白 | MCE
UCHL1 蛋白是一种泛素羧基末端水解酶，在蛋白质降解和细胞过程调节中发挥着至关重要的作用。 它参与维持神经元完整性并与神经退行性疾病有关。 UCHL1 蛋白作为神经退行性疾病的生 …
UCHL1 Gene - GeneCards | UCHL1 Protein | UCHL1 Antibody
2024年12月25日 · UCHL1 (Ubiquitin C-Terminal Hydrolase L1) is a Protein Coding gene. Diseases associated with UCHL1 include Spastic Paraplegia 79B, Autosomal Recessive and …
Ubiquitin C-terminal hydrolase-L1 (UCH-L1) as a therapeutic and ...
Since its discovery as a major CNS-abundant protein 25 years ago, Ubiquitin C-terminal hydrolase-L1 (UCH-L1) has emerged as an important enzyme in regulating brain protein …
泛素 C 末端水解酶 L1 (UCH-L1)：结构、分布和在脑 ... - X-MOL
UCH-L1 对神经元发育不是必需的，但它是维持轴突完整性所必需的，并且 UCH-L1 功能障碍与神经退行性疾病有关。 在这里，我们回顾了 UCH-L1 的特性， Ubiquitin C-terminal hydrolase …
Ubiquitin C‑terminal hydrolase‑L1: A new cancer marker and …
Ubiquitin C-terminal hydrolase-L1 (UCH-L1), a member of the lesser-known deubiquitinating enzyme family, has deubiquitinase and ubiquitin (Ub) ligase activity and the role of stabilizing …
Cell Reports丨UCH-L1 是巨噬细胞中 NLRP3 介导的 IL-1β 生成的重 …
uch-l1 催化抑制可抑制 asc 组装、nlrp3 炎症小体激活和 il-1β 处理. 为了研究 uch-l1 如何调节 il-1β 的处理和释放，作者选择了一种强效抑制剂 imp-1711-s（图 7a）并测试了它对 thp-1 细胞、 …