UCP1 is a member of the superfamily of mitochondrial carrier proteins (see Figure 43-2, B). 59-61 Most closely related to UCP1 are two more recently identified but evolutionarily more ancient …

2001年3月1日 · The UCP1 content in brown adipose tissue (whether determined as mRNA level, GDP binding or protein) is increased following these dietary challenges [16]. Thus, the …

2023年9月1日 · Liraglutide elevates UCP1 content rather than UCP1 mRNA expression, whereas CL316243 increases UCP1 mRNA expression that ultimately increase thermogenesis. 32 …

2017年3月1日 · Following the sequencing of our rat UCP1 cDNA in 1985 we also predicted, almost simultaneously, the amino acid sequence of the rat UCP1 and presented a sequence …

2017年3月1日 · UCP1 is a monomer binding GDP with a 1:1 stoichiometry. (A) Assessment of the molecular mass of UCP1 in 10MNG/cardiolipin by size exclusion chromatography [36]. Inset …

2017年3月1日 · After several decades of research, we have come to recognize three major features of UCP1 protein expression in relation to the biology of BAT that ultimately rely on …

2024年9月3日 · Although UCP1 mRNA expression showed a trend toward correlating with energy expenditure and oxygen consumption under cold conditions (Figures 5 C and 5E), it should be …

2024年7月25日 · UCP1 is primarily located in the inner mitochondrial membrane of brown adipose tissue (BAT) and beige adipocytes. It is normally inactive and does not generate heat unless …

2022年3月1日 · Among UCPs, UCP1 is primarily reported in the mitochondria of BAT that play an essential role in the regulation of energy expenditure, thermogenesis, mitochondrial …

2017年3月1日 · The purified UCP1 formed a platform for studying the parameters governing the activation and the inhibition of the uncoupling, independently of the complex environmental …