UGT超家族是植物界最大的糖基转移酶基因家族(Rehman 等2018; Song 等2019), 从结构最简单的单细胞藻类至苔藓、蕨类及高等植物中均广泛存在。根据系统发育特征, UGT 可分为A~Q 共17个组(Rehman 等2018), 其中氨基酸序列相似性达到40% 即可划分为同一UGT 家族, 达到60%为同一 ...

2024年3月4日 · Despite extensive studies on the UGT gene family in various species, a comprehensive investigation of the UGT family in P. bournei has not been reported. Therefore, we conducted a systematic analysis to identify 156 UGT genes within the entire P. bournei genome, all of which contained the PSPG box.

2023年12月7日 · The UGT multigene family has been profiled in a variety of plant species, such as Arabidopsis [56], wheat [57], grape [58] and peach [59]. In current study, a systematic analysis of the UGT family was conducted in peanut, and 267 AhUGT genes have been identified.

2019年4月1日 · This review summarizes and provides critical analysis of the current state of research into all four families of UGT enzymes. Key areas discussed include the roles of UGTs in drug metabolism, cancer risk, and regulation of signaling, as well as the transcriptional and posttranscriptional control of UGT expression and function.

2024年12月18日 · UGT gene family has been identified in many species to date. However, the comprehensive identification and systematic analysis have not been documented yet in the latest potato genome. In this study, a total of 295 UGT members (StUGT) were identified and found to be unevenly distributed on twelve chromosomes of potato.

UDP-glycosyltransferases (UGTs) are a superfamily of enzymes found in animals, plants, fungi, and germs that catalyze the covalent addition of sugars from nucleotide UDP sugar donors to functional groups on a variety of lipophilic compounds. There are 22 UGTs in humans.

2022年12月1日 · The expression profiles of UGT genes in various tissues of E. pubescens were analyzed using RNA-seq. Specifically, a novel flavonoid UGT gene (named EpGT60) was revealed to encode a key UGT to catalyze the rhamnosylation of prenylflavonols at the 3-OH position in in vitro enzymatic assays.

The results of this study clearly show that the UGT family expanded during the transition from algae to vascular plants and that in higher plants the clustering of UGTs into phylogenetic groups appears to be conserved, although gene loss and gene gain events seem to have occurred in certain lineages.

UGTs (UDP glycosyltransferase) are the largest glycosyltransferase gene family in higher plants, modifying secondary metabolites, hormones, and xenobiotics. This gene family plays an important role in the vast diversity of plant secondary metabolites specific to species.

2024年1月15日 · The UDP-glycosyltransferase (UGT) family is known for having the largest number of glycosyltransferases, and research has highlighted the fundamental role of UGT family members in both plant development and stress response.