L’Institut de recherche en santé digestive rassemble et structure des forces de recherche autour d’un but commun : améliorer la compréhension de la physiologie du tractus digestif.

Avoir rassemblé en un même lieu des expertises sur la fonction de la barrière intestinale, le microbiote, l'immunologie des muqueuses, la neurogastroentérologie et le métabolisme du fer …

Here, we investigated the effect of lipid-free APOA1 and the involvement of ecto-F 1 -ATPase and P2Y ADP receptors on nitric oxide (NO) synthesis and the regulation of vascular tone. Method: Nitric oxide synthesis was assessed in human endothelial cells from umbilical veins (HUVECs) and isolated mouse aortas.

Sigle : UMR 1220 | UMR 1416 Ville : TOULOUSE CEDEX 03 Pays : France

Date de la dernière mise à jour : 08/12/2016

Plateforme de l' Institut de Recherche en Santé Digestive (IRSD) INSERM (UMR 1220)-INRAE (UMR 1416)-ENVT-UT

2023年11月23日 · Here, we investigate the impact of perinatal foodborne TiO 2 exposure on the intestinal mucosal function and the susceptibility to develop IBD-associated colitis.

2021年7月30日 · The aim of this review is to provide a critical opinion on the potential of TiO 2 particles, especially when used as a food additive, to alter the four elements of the intestinal barrier function, and consequently to evaluate if this additive would likely play a role in the development and/or exacerbation of IBD.

Department of digestive surgery, colorectal surgery unit, Toulouse University Hospital, Toulouse, France. Corresponding Author: Dr. Etienne BUSCAIL, MD, PhD, INSERM, UMR-1220, IRSD, Place du Dr. Baylac, CHU Toulouse Purpan, CS 60039, Toulouse 31024, Cedex 3, France;[email protected]

For digestive purposes, the lumen of the upper GI tract contains large amounts of pancreatic proteases, but studies have also demonstrated increased proteolytic activity into mucosal tissues (both in the upper and lower GI tract), associated with pathological conditions.