
USP9X - Wikipedia
USP9X is a protein-coding gene that has been implicated either directly through mutations or indirectly in a number of neurodevelopmental and neurodegenerative disorders. Three …
USP9X Gene - GeneCards | USP9X Protein | USP9X Antibody
2024年12月25日 · USP9X (Ubiquitin Specific Peptidase 9 X-Linked) is a Protein Coding gene. Diseases associated with USP9X include Intellectual Developmental Disorder, X-Linked 99, …
Dev Cell | 王晓虹团队揭示去泛素酶USP9X通过Wnt信号通路影响中 …
2025年2月4日,天津医科大学基础医学院药理学系的 王晓虹 教授团队在 Developmental Cell 杂志上在线发表了题为 Deubiquitinase USP9X controls Wnt-signaling for CNS vascular formation …
USP9X regulates centrosome duplication and promotes breast
2017年3月31日 · We demonstrate that USP9X is an integral component of centrosome and is required for centrosome biogenesis. Loss-of-function of USP9X impairs centrosome …
The X-linked deubiquitinase USP9X is an integral component of ...
In this study, we utilized the tandem mass tag labeling assay to identify USP9X-regulated proteins and revealed that the expression of multiple genes is altered in USP9X-deficient cells. …
USP9X ubiquitin specific peptidase 9 X-linked [ (human)]
USP9X is a key deubiquitinase for ALDH1A3 protein stabilization and a potential target for glioblastoma stem cell-directed therapy; show that USP9X-mediated BCL9 deubiquitination …
Roles of USP9X in cellular functions and tumorigenesis (Review)
Ubiquitin-specific peptidase 9X (USP9X) is involved in certain human diseases, including malignancies, atherosclerosis and certain diseases of the nervous system. USP9X promotes …
The deubiquitinase Usp9x regulates PRC2-mediated chromatin
2021年3月25日 · Using an auxin-inducible degron system, we show that the deubiquitinase Usp9x is required for mouse embryonic stem (ES) cell self-renewal. Usp9x-high ES cells have high …
泛素特异性肽酶 9 X-连锁(USP9X)基因 - MCE-生物活性 ...
该基因是肽酶 C19 家族的成员,编码一种类似于泛素特异性蛋白酶的蛋白质。 虽然这个基因位于 X 染色体上,但它逃避了 X 失活。 该基因的突变与特纳综合征有关。 已经表征了编码不同亚型 …
去泛素酶USP9X稳定PTGES并通过PGE2信号传导促进肺癌的转移特 …
2023年7月19日 · USP9X与PTGES发生物理相互作用,并防止其通过去泛素化作用进行蛋白酶体定向降解。 与此一致,USP9X表达与NSCLC肿瘤组织中的PTGES表达高度相关。 总之,作者 …
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