UDCA is a bile acid which effects a reduction in cholesterol in biliary fluid primarily by dispersing the cholesterol and forming a liquid-crystal phase. UDCA affects the enterohepatic circulation …

Ursodeoxycholic acid (UDCA), also known as ursodiol, is a secondary bile acid, produced in humans and most other species from metabolism by intestinal bacteria.

Our research group developed and validated a simple, fast, specific, exact, and robust method with HPLC-UV for the determination and quantification of UDCA in raw materials and liquid …

2014年12月30日 · This paper describes a rational method of characterizing the biopharmaceutical stability of two oral suspensions of ursodeoxycholic acid (UDCA) used in pediatrics. Because …

The objective of this study is to present a new liquid formulation of ursodeoxycholic acid (UDCA) at a concentration suitable for treatment of neonatal jaundice, and to introduce a novel high …

2024年3月11日 · The removal of endogenous UDCA, GUDCA, and TUDCA was confirmed using liquid chromatography–tandem mass spectrometry (LC–MS/MS). Calibration standard …

2001年3月1日 · Ursodeoxycholic acid (3α, 7β-dihydroxy-5β-cholanoic acid, UDCA) is a therapeutically applicable bile acid widely used for the dissolution of cholesterol-rich gallstones …

The hexafluoroisopropyl trifluoroacetate ester derivative of UDCA was selected for GC analysis since it is easily and rapidly prepared by a one-step reaction. Biliary UDCA levels were …

Ursodeoxycholic acid (UDCA) (3α, 7β- dihydroxy-5β-cholan-24-oic acid), (Figure 1), also known as ursodiol, is a naturally occurring bile acid (BA). BAs are steroid compounds, hydroxyl …

We studied liquid crystal formation in bile samples obtained from the patients with radiolucent gallstones who had been administered either ursodeoxycholic acid (UDCA) at a dose of 600 …