Ursodeoxycholic acid treatment in a rat model of cancer cachexia
Ursodeoxycholic acid (UDCA), a bile acid used for centuries in the treatment of liver disease, is known to confer anti-inflammatory and anti-apoptotic effects as well as beneficial effects on …
Evaluating the effect of ursodeoxycholic acid (UDCA) in …
In this study, we demonstrated the effectiveness of UDCA compared with dexamethasone and diclofenac as a treatment for arthritis in a rat model induced by Freund's complete adjuvant …
Evaluating the effect of ursodeoxycholic acid (UDCA) in
Ursodeoxycholic acid (UDCA) is known for its major effects on the liver, but its impact on autoimmune diseases is not well understood. This study aimed to assess the effectiveness of …
Ursodeoxycholic acid alleviates nonalcoholic fatty liver disease …
2020年8月27日 · Our finding revealed that UDCA exerted obviously favorable influence on hepatic steatosis in NAFLD rats by activating AMP-activated protein kinase (AMPK). …
Ursodeoxycholic acid attenuates 5-fluorouracil-induced mucositis …
2018年6月4日 · Ursodeoxycholic acid (UDCA) stabilizes cell membranes, acts as an antioxidant and inhibits apoptosis, thereby exerting cytoprotective effects. The aim of the present study …
Development of UHPLC‐MS/MS Method for Evaluation of the …
2024年11月19日 · The acute oral toxicity and the pharmacokinetic studies were conducted using 17 rats divided into five groups and 30 rats assigned into four control groups and one …
Ursodeoxycholic and chenodeoxycholic bile acids alleviate ...
2025年3月6日 · Introduction: This study aimed to investigate the anti-inflammatory, antioxidant, and anti-apoptotic properties of ursodeoxycholic (UDCA) and chenodeoxycholic (CDCA) bile …
Mitochondria-targeted nanovesicles for ursodeoxycholic acid …
2025年3月11日 · Ursodeoxycholic acid (UDCA), a clinical drug used for liver disease, possesses antioxidant and mitochondrial repair properties. Recently, it has gained attention as a potential …
A Mechanistic Study of the Feasibility of Ursodeoxycholic Acid in …
Bile acids promote the progression of colon adenocarcinoma (COAD), and ursodeoxycholic acid (UDCA) is a key drug in promoting bile acid excretion, but its role in COAD unclear. ...
The Potential Therapeutic Approach of Ursodeoxycholic Acid as a …
2024年12月11日 · The present investigation assesses ursodeoxycholic acid's efficacy (UDCA) as an ACE2 activator against gamma irradiation through activating the renin-angiotensin system's …
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