Hyphen Biomed USP-EP Anti‐Factor Xa and Anti‐Factor IIa Assay Buffers available for Unfractionated and Low Molecular Weight Heparins. For the Anti-Xa 2-stage assay, for performing the method in compliance with the new USP or EP guidances, the needs are summarized in the table below, for LMWH or UFH:

2023年4月3日 · Unfractionated heparin (UFH) binds to antithrombin III (AT-III), which enhances antithrombin's inhibition of several coagulation factors – especially factor Xa and factor IIa (thrombin). Low Molecular-Weight Heparin (LMWH) is a heterogeneous collection of heparin molecules with a lower average molecular weight compared to unfractionated heparin.

2013年7月3日 · Our in vitro study showed that EP217609C101 is a promising new drug that is dose-dependently superior to classical (UFH, enoxaparin) and newer (fondaparinux) drugs in preventing heart catheter thrombosis.

Smart Buffers by Medicago available in pre-measured pouches for use with compendial tests. *PEG or BSA buffer can be used in USP test for LMWH. Use charts below to determine the buffer needed for specific assay.

Kits compatible with USP and EP monograph test requirements; Easy-to-use automated and manual test protocols available, with applications for all major hemostasis instruments; Unsurpassed technical guidance and support; Testing Products Available

For use as dilution buffer for standards, samples, AT, FXa, thrombin, and blank in USP and EP methods for Anti-FXa and Anti-FIIa activity assays for Unfractionated Heparin (UFH). USP = United States Pharmacopeia. EP = European Pharmacopoeia.

2024年4月1日 · Patients with higher-risk PE may require advanced interventions such as thrombolytic therapy, surgical thrombectomy, or even extracorporeal membrane oxygenation (ECMO). Because of its short half-life and availability of a reversal agent, unfractionated heparin (UFH) is commonly used when percutaneous or surgical interventions are being considered.

2010年10月7日 · Anticoagulation with heparin is widely considered the standard initial therapy for patients with acute cerebral venous thrombosis (CVT), but there is no consensus on which type of heparin to use: unfractionated or low–molecular weight heparin. 1–4 Unfractionated heparin (UFH) is administered intravenously and requires dose adjustments based ...

2020年9月3日 · To assess the association between low-molecular weight heparin (LMWH) and unfractionated heparin (UFH) in the prevention of venous thromboembolism (VTE) among participants undergoing general surgery. LMWH and UFH are the standard of practice in the prevention of VTE in surgery.

USP‐EP ANTI‐FXa AND ANTI‐FIIa ASSAY BUFFERS Smart Buffers (by Medicago) in pre‐measured pouches for use with the following compendial tests: USP39: <208> Anti‐Factor Xa and Anti‐Factor IIa Assays for Unfractionated and Low Molecular Weight Heparins