USP21 Gene - GeneCards | UBP21 Protein | UBP21 Antibody
2024年12月25日 · USP21 (Ubiquitin Specific Peptidase 21) is a Protein Coding gene. Diseases associated with USP21 include Variegate Porphyria. Among its related pathways are TNF …
Insights Into the Properties, Biological Functions, and Regulation of USP21
In the present review, we provide a comprehensive overview of the current knowledge on USP21, including its properties, biological functions, pathophysiological roles, and cellular regulation.
USP21 ubiquitin specific peptidase 21 [ Homo sapiens (human) ]
2025年2月8日 · Title: USP21 accelerates the proliferation and glycolysis of esophageal cancer cells by regulating the STAT3/FOXO1 pathway. USP21 promotes self-renewal and …
USP21 deubiquitinates and stabilizes HSP90 and ENO1 to …
2024年2月4日 · In vivo and in vitro, we identified USP21 as a master regulator of CCA growth and maintenance, which directly interacted with deubiquitinates and stabilized the heat shock …
The emerging role of deubiquitylating enzyme USP21 as a …
2024年6月1日 · Research findings from the past decade demonstrate that USP21 mediates the deubiquitination of multiple well-known target proteins associated with critical cellular …
Discovery and Characterization of BAY-805, a Potent and Selective ...
2023年2月20日 · USP21 interacts with, deubiquitinates and stabilizes BRCA2 to promote efficient RAD51 loading at DNA double-strand breaks. As a result, depletion of USP21 decreases …
The deubiquitinase USP21 maintains the stemness of mouse
2016年11月25日 · Here we report that the deubiquitinase USP21 interacts with, deubiquitinates and stabilizes Nanog, and therefore maintains the protein level of Nanog in mouse ESCs …
Ubiquitin-specific protease 21 stabilizes BRCA2 to control DNA
2017年7月26日 · Here, we identify the ubiquitin-specific protease USP21 as a positive regulator of BRCA2, a key mediator of DNA repair by homologous recombination. USP21 interacts with, …
The ubiquitin-specific protease 21 is critical for cancer cell ...
2024年4月12日 · Enzymatic activity of USP21 regulates protein degradation which is critical for maintaining cell homeostasis. USP21 determines the stability of oncogenic proteins and …
USP21 promotes self-renewal and tumorigenicity of mesenchymal …
2022年8月16日 · In this study, we identify the ubiquitin-specific peptidase 21 (USP21) as a critical FOXD1 deubiquitinase in MES GSCs. We find that USP21 directly interacts with and stabilizes …