2025年3月3日 · Results: This study successfully achieved the combined detection of structural and functional connectivity in the V1 of mice. The rAAV1-hSyn-Cre virus was utilized for …

2017年1月4日 · To test this, we first optogenetically activated the axon terminals of SC-sg neurons in LP (Figure 7D) in freely behaving mice, which resulted in similar, though somewhat …

分别在sc的上游视皮层、视网膜、听皮层及运动皮层注射aav1-cre，在sc注射aav1-cag-flex-gfp；可以看出被标记的不同上游支配的sc神经元所支配的下游也各有不同。

2020年4月20日 · Recombinant adeno-associated viruses (rAAVs) are efficient gene delivery vectors via intravenous delivery; however, natural serotypes display a finite set of...

2022年2月21日 · As a proof-of-principle, we aimed to demonstrate that postsynaptic neurons receiving both monosynaptic inputs can be selectively labelled in two distinct circuits: the …

2023年7月19日 · This study reveals the presence of a system of lateral HVAs that depends on the SC and that, in contrast to V1, responds preferentially to stimuli with positive visuo-motor …

Here we describe the use of adeno-associated virus, serotype 1 (AAV1) as a tool for achieving robust, anterograde transsynaptic spread in a variety of unidirectional pathways.

2022年8月8日 · We injected the original virus (AAV1-hSyn-Cre) or the mutant virus (AAV1YF-hSyn-Cre) into the V1 region of Ai14 mice that express tdTomato under the presence of Cre …

Following two-step injection of AAV1-hSyn-Cre in either visual cortex (V1), retina, auditory cortex (A1), or primary motor cortex (M1) and AAV1-CAG-FLEX-GFP in SC, distinct patterns of axon …

2021年1月25日 · 目前常用的顺行跨单级突触示踪病毒主要有两种：HSV-1-H129- TK和AAV1。 HSV-1-H129- TK 是将HSV-1-H129复制所需的TK基因缺失掉，当感染神经元后，HSV-H129- …