Membrane accumulation of AQP2 could result from a VP-induced increase in exocytosis, a decrease in endocytosis, or both. In the present study, we further investigated AQP2 …

Aquaporin-2 (AQP-2) has been shown to be a vasopressin-sensitive water channel in collecting duct (CD) cells of the kidney. To prove the role of the vasopressin V2 receptor (V2R) in the …

2021年7月1日 · Targeting the collecting duct water channel aquaporin 2 (AQP2) to the plasma membrane is essential for the maintenance of mammalian water homeostasis. The …

2014年5月1日 · The arginine vasopressin (AVP) type 2 receptor (V2R) is unique among AVP receptor subtypes in signaling through cAMP. Its key function is in the kidneys, facilitating the …

2025年1月1日 · AVP activates V2R, stimulating the formation of cyclic adenosine monophosphate (cAMP) and enhances the production of intratubular Ang II via distal tubule renin through V2R [7].

结果：益气活血利 水法可降低心衰大鼠血浆中AVP浓度，减弱肾组织V2R、AQP-2蛋白表达，降低V2R、AQP2、mRNA相对表达量。 结论：益气 活血利水法通过作用于精氨酸血管加压素-V2 …

Membrane accumulation of AQP2 could result from a VP-induced increase in exocytosis, a decrease in endocytosis, or both. In the present study, we further investigated AQP2 …

2012年10月1日 · Vasopressin binds to its type 2 receptor (V2R) that is located in the basolateral membrane of collecting duct principal cells, and binding triggers the trafficking of AQP2 …

近年来许多研究表明，梅尼埃病患者血浆AVP水平超常地增高，AVP可能通过V2R-cAMP-AQP2信号系统，使内耳AQP2表达升高，降低内淋巴囊上皮对水的重吸收，最终导致膜迷路积水，从 …

Arginine vasopressin (AVP) is essential for maintaining body fluid homeostasis. The antidiuretic effects of AVP are initialized by binding of AVP to the type-2 vasopressin receptor (V2R) in the …