Hepatic veno-occlusive disease (VOD) or veno-occlusive disease with immunodeficiency is a potentially life-threatening condition in which some of the small veins in the liver are obstructed. It is a complication of high-dose chemotherapy given before a bone marrow transplant or excessive exposure to hepatotoxic pyrrolizidine alkaloids .

2019年5月4日 · Sinusoidal obstruction syndrome (SOS), previously known as veno-occlusive disease (VOD), is a distinctive and potentially fatal form of hepatic injury that occurs predominantly, if not only, after drug or toxin exposure.

Hepatic veno-occlusive disease (VOD) or sinusoidal obstruction syndrome (SOS) is a rare complication characterized by hepatomegaly, right-upper quadrant pain, jaundice, and ascites, occurring after high-dose chemotherapy, hematopoietic stem cell transplantation (HSCT) and, less commonly, other conditions.

What is VOD? Hepatic veno-occlusive disease (VOD) is a complication that affects the liver and can occur following stem-cell transplant. VOD may also be referred to as sinusoidal obstruction syndrome, or SOS, by the transplant team. Lungs Liver Kidneys VOD begins in the liver and can quickly affect other vital organs, most notably

2024年5月16日 · Sinusoidal obstruction syndrome (SOS), previously known as hepatic veno-occlusive disease (VOD), is a condition arising from occlusion of hepatic venules. Toxic injury to liver sinusoids causes sloughing of endothelial cells that embolize to hepatic venules and cause eventual fibrosis of the venules.

Hepatic veno-occlusive disease (VOD) is a complication that affects the liver and can occur following stem-cell transplant. VOD may also be referred to as sinusoidal obstruction syndrome, or SOS, by the transplant team. VOD begins in the liver and can quickly affect other vital organs, most notably the kidneys and lungs.

2023年12月15日 · 肝小静脉闭塞病（hepatic veno-occlusive disease，VOD） 是由于某些原因所致 肝小叶中央静脉和小叶下静脉等小静脉内膜炎和纤维化，而导致管腔狭窄、广泛闭塞，甚至引起肝细胞坏死、纤维化的一种血管疾病。

Hepatic veno-occlusive disease (VOD) or sinusoidal obstructive syndrome (SOS) is a disorder characterised by obstruction of small intra-hepatic venules and damage to the surrounding centrilobular hepatocytes and sinusoids. It occurs principally as a complication of chemo-irradiation therapy, particularly following BMT.

肝小静脉闭塞病 (VOD)又称肝窦阻塞综合征 (SOS)，是进行造血干细胞移植 (HSCT)期间发生的一种严重的并发症，其特征为肝肿大、疼痛、黄疸和腹水。 HSCT后VOD/SOS的中位发生率为13.7% (0~62%) [1]。 严重的VOD/SOS的定义是存在多器官功能障碍 (MOD)，包括肾功能衰竭 (血清肌酐≥正常值3倍或需要血液透析)或呼吸衰竭 (室内空气氧饱和度<90%，或需依赖呼吸机)，并与更高的死亡率 (>80%)相关 [2]。 肝脏窦状内皮损伤在VOD/SOS的发病机制中起核心作用，内皮损伤 …

General signs and symptoms of veno-occlusive disease (VOD) include: Pain and tenderness in the abdomen , especially on the upper right side, due to swelling of the liver , known as hepatomegaly Rapid weight gain compared to your weight when you …