
Cell | 人类大脑进化的新机制:神经祖细胞形态的变化促进皮层祖 …
Rakic等人的研究揭示了大脑皮层发育起始于胚胎神经系统的脑室区(ventricular zone,vz)的神经上皮细胞(neuroepithelial cells,也称为神经上皮祖细胞progenitor cells,NE或NPC)。 …
Molecular Identity of Human Outer Radial Glia during ... - Cell Press
2015年9月24日 · Radial glia, the neural stem cells of the neocortex, are located in two niches: the ventricular zone and outer subventricular zone. Although outer subventricular zone radial glia …
oRGs and mitotic somal translocation — a role in development …
As oRG cells share many molecular features with ventricular radial glial (vRG) cells, an examination of the defining features of vRG cells is essential for gaining a comprehensive …
Development and Evolution of the Human Neocortex - Cell Press
2011年7月8日 · Recent studies show that development of the gyrated human neocortex involves a lineage of neural stem and transit-amplifying cells that forms the outer subventricular zone …
【学术前沿】Cell:焦建伟/董骥/杜鹏/靳蕾团队合作解析迄今最全 …
2023年12月12日,中国科学院动物研究所焦建伟团队、广州国家实验室董骥团队、北京大学杜鹏团队和北京大学靳蕾团队合作在Cell杂志在线发表了题为Spatiot
Mitotic spindle orientation predicts outer radial glial cell …
2013年4月9日 · Evolutionary changes in mitotic spindle orientation could have altered the way cell fate determinants are segregated during vRG cell mitosis, affecting daughter cell fate and …
Lysosomal dynamics regulate mammalian cortical neurogenesis - Cell …
2024年1月8日 · The radial glial cell (RGC) serves as the main neural progenitor cell that symmetrically divides to expand the stem cell pool or asymmetrically divides to generate a self …
Fixed single-cell transcriptomic characterization of human
2015年11月4日 · Our study identified vRG and oRG markers and molecular profiles, an essential step for understanding human neocortical progenitor development. FRISCR allows targeted …
Cell:打开大脑神经发育研究的新大门 - 知乎 - 知乎专栏
文章在最新一期的Cell杂志上发表,名为“Purification and characterization of human neural stem and progenitor cells”。 最近,单细胞技术提供了前所未有的空间和时间分辨率,使得神经干细 …
Cell:焦建伟/董骥/杜鹏/靳蕾合作解析迄今最全人脑多区域时空发 …
2023年12月13日 · 该研究将单细胞测序(scRNA-seq)和空间转录组技术(scStereo-seq)相结合,首次解析了迄今为止跨时间点最广(GW6-GW23)、面积最大(最大4cm × 3cm)的人脑 …