Dec 25, 2024 · VCX2 (Variable Charge X-Linked 2) is a Protein Coding gene. Diseases associated with VCX2 include Ichthyosis, X-Linked and Phlyctenulosis. An important paralog of this gene is VCX3A. May mediate a process in spermatogenesis or may play a role in sex ratio distortion. ( VCX2_HUMAN,Q9H322 ) ... Belongs to the VCX/VCY family.

Feb 26, 2025 · VCX2, a cancer/testis antigen, emerged as a potential biomarker and druggable target due to its altered expression among multiple cancers. Structural modeling and molecular docking (MD) of VCX2 identified a high affinity binding pocket, guiding a virtual screening of Peruvian natural products.

Identification of novel tumor-specific targets is important for the future development of immunotherapeutic strategies using genetically engineered T cells or vaccines. In this study, we characterized the expression of VCX2, a member of the VCX/Y ...

Feb 8, 2021 · In this study, we characterized the expression of VCX2, a member of the VCX/Y cancer/testis antigen family, in a large panel of normal tissues and tumors from multiple cancer types using immunohistochemical staining and RNA expression data.

Feb 9, 2021 · Identification of novel tumor-specific targets is important for the future development of immunotherapeutic strategies using genetically engineered T cells or vaccines. In this study, we characterized the expression of VCX2, a member of the VCX/Y cancer/testis antigen family, in a large panel of nor …

Feb 8, 2025 · This gene belongs to the VCX/Y gene family, which has multiple members on both X and Y chromosomes that are expressed exclusively in male germ cells. The VCX gene cluster is polymorphic in terms of copy number; different individuals may have a different number of VCX genes. This gene contains two copies of a 30 nt tandem repeat.

In this study, we characterized the expression of VCX2, a member of the VCX/Y cancer/testis antigen family, in a large panel of normal tissues and tumors from multiple cancer types using immunohistochemical staining and RNA expression data.

Clinical resource with information about VCX2, and available tests. There are links to practice guidelines and authoritative resources like GeneReviews, PubMed, MedlinePlus, PharmGKB and clinicaltrials.gov.

Selective nuclear expression in spermatogonia, spermatocytes and spermatids. Main subcellular location based on data generated in the subcellular section of the Human Protein Atlas.

RefSeq summary [VCX2] This gene belongs to the VCX/Y gene family, which has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. The X-linked members are clustered on chromosome Xp22 and Y-linked members are two identical copies of the gene within a palindromic region on Yq11.