V (D)J recombination (variable–diversity–joining rearrangement) is the mechanism of somatic recombination that occurs only in developing lymphocytes during the early stages of T and B …

2018年11月29日 · We present the largest-to-date VDJH gene repertoire analysis in MM, consisting in biological and clinical data from 413 patients.

2001年11月1日 · In the present study, we report on the gene scanning technique for size fragment analysis of VDJH-rearranged products in order to detect clonally rearranged cells in …

The gene scanning of clonally rearranged VDJ segments of the heavy chain immunoglobulin gene (VDJH) is a reproducible and easy to perform technique that can be optimised for clinical …

2018年11月29日 · VDJH usage somatic hypermutation levels and CDR3 composition in multiple myeloma resembles the normal mature B cell repertoire. In contrast to Chronic Lymphocytic …

2020年2月6日 · Here, we present the largest-to-date analysis of the VDJH repertoire in multiple myeloma, consisting in biological and clinical data from 413 patients diagnosed and treated …

2000年8月4日 · In the present paper, we report on the use of the heteroduplex PCR technique to detect the presence of clonally rearranged VDJ segments of the heavy chain immunoglobulin …

In the present paper, we report on the use of the heteroduplex PCR technique to detect the presence of clonally rearranged VDJ segments of the heavy chain immunoglobulin gene …

互补决定区是VL与VH均有3个HVR，它们共同组成Ig的抗原结合部位（antigen-binding site）。 该部位因在空间结构上可与抗原决定簇形成精密的互补，故超变区又称互补性决定区 …

1989年9月8日 · We have constructed a hybrid immunoglobulin (VDJH)-T cell receptor (C alpha) gene using the VDJH exon from a digoxin-specific antibody. This gene was used to make a …